Ketamine is a useful sedative and antidepressant at light doses. At stronger doses, it is a powerful anesthetic, but at repeated high doses, it deadens sensation, leaving users conscious but unable to act.
An H.I.V. awareness poster displayed in Suva, Fiji, in April. The nation recorded more than 2,000 new cases in 2025, 16 times as many as in 2019, officials said.
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