Francis Halzen, a physicist at the University of Wisconsin, Madison, has won the 2026 Nobel Prize in Physics "for decisive contributions to the IceCube Neutrino Observatory and the discovery of high-energy neutrinos of astrophysical origin.” Halzen spearheaded the development and construction of the IceCube Neutrino Observatory in Antarctica, enabling physicists to capture high-energy neutrinos created in the distant universe.

“It was a great surprise, and I obviously didn’t expect it,” Halzen said during a news conference in Stockholm, Sweden, speaking by phone from Italy. While the Nobel was awarded to Halzen, he emphasized that his work was the result of a “large collaboration” with other researchers.

“This reflects on the really courageous people who joined me in this project when really no respectable conservative physicist would have joined me. But many talented people did, and that’s why I’m here,” he said.

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Quarantine measures have been in place in several hospitals in eastern Russia since a 28-year-old laboratory worker, Darya Shipilova, died after falling ill at work following a reported accident at a plague research centre in Siberia. Russia’s health watchdog has said she died of ‘pneumonia of unknown aetiology’, but there is speculation about a possible plague infection. Lucy Hough speaks to Science Weekly co-host Madeleine Finlay

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© Photograph: Guardian Design

© Photograph: Guardian Design

© Photograph: Guardian Design

Firms working on reproducing compounds without need for repeated harvesting but conservationists are sceptical

Many of the world’s most expensive perfumes begin with a wounded tree. When some Aquilaria trees are damaged, they produce a dark, fragrant resin that becomes agarwood, or oudh – an ingredient so valuable that wild trees have been illegally felled in its pursuit.

The result has devastated wild Aquilaria populations. But what if perfumers could create the smell without cutting down the tree?

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© Photograph: Pixel-shot/Alamy

© Photograph: Pixel-shot/Alamy

© Photograph: Pixel-shot/Alamy

Over decades of research, scientists have built up a partial picture of what specialized cells within the brain and spinal cord do. By studying how the brain develops, they could identify genes that were active in different populations of neurons and where in the brain those neurons resided. In some cases, these genes could then be used to genetically delete the neurons, allowing us to get some indication of what they might be doing, building on the information we've obtained from studies of brains with damaged regions.

But this approach has its limits. The brain is flexible enough to potentially adapt to the loss of some cells, and their loss early in development may alter the development of any neurons they would have normally formed connections with. It would be far more informative to activate and shut down the neurons in an otherwise intact brain.

Today's Nobel Prize in Physiology or Medicine rewards three people—Karl Deisseroth, Peter Hegemann and Georg Nagel—who developed our ability to do precisely that. Starting from studies of single-celled algae that are attracted to light, these and many other researchers built an entire field of study that we now call optogenetics: using light to alter the behavior of nerve cells marked by the activity of individual genes.

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We asked 100 scientists about unsolved problems in their fields. They sent back provocations — on the origins of life, the possibilities for human progress and much more.

© Photo illustration by Jane Stockdale for The New York Times