Psychiatry professor theorizes that the difference is related to how the substances interact with areas of the brain
A recent review of alternative treatments for obsessive compulsive disorder (OCD) indicates that psychedelic treatments show promise for the disorder while cannabis does not.
Dr Michael Van Ameringen, a psychiatry professor at McMaster University in Ontario, Canada and lead author of the review published in the Journal of Psychiatric Research, said that 40-60 % of OCD patients get either partial or no relief with available treatments, including SSRIs and exposure and response prevention therapy.
Health secretary wrote to Conservative leader Kemi Badenoch, urging her to ‘take heat and ideology’ out of debate
The health secretary, Wes Streeting, has called on the Conservatives to maintain the cross-party consensus on gender identity services built before the last election in a letter to Kemi Badenoch.
Streeting wrote to opposition leader on Friday urging her to “take the heat and the ideology” out of debate amid controversy over a puberty blocker trial for children.
Dense, 450-mile-long fog bank lingering over central valley as experts blames unusual combination of weather factors
New Nasa satellite images reveal the scope of central California’s dreary December, caused by an enormous fog formation that has been haunting the Central Valley for weeks, trapping residents in colder-than-usual temperatures.
The low cloud formation, known as tule fog, first formed over central California in November and persisted into early December. The Central Valley typically sees this type of fog during the colder months of the year, when the air near the ground is cold and moist, and the winds are calmer, allowing moisture in the air to transform into a thick layer of fog.
For the first time, global governments have agreed to widespread international trade bans and restrictions for sharks and rays being driven to extinction.
Last week, more than 70 shark and ray species, including oceanic whitetip sharks, whale sharks, and manta rays, received new safeguards under the Convention on International Trade in Endangered Species of Wild Fauna and Flora. The convention, known as CITES, is a United Nations treaty that requires countries to regulate or prohibit international trade in species whose survival is threatened.
Sharks and rays are closely related species that play similar roles as apex predators in the ocean, helping to maintain healthy marine ecosystems. They have been caught and traded for decades, contributing to a global market worth nearly $1 billion annually, according to Luke Warwick, director of shark and ray conservation at Wildlife Conservation Society (WCS), an international nonprofit dedicated to preserving animals and their habitats.
Modern bionic hand prostheses nearly match their natural counterparts when it comes to dexterity, degrees of freedom, and capability. And many amputees who tried advanced bionic hands apparently didn’t like them. “Up to 50 percent of people with upper limb amputation abandon these prostheses, never to use them again,” says Jake George, an electrical and computer engineer at the University of Utah.
The main issue with bionic hands that drives users away from them, George explains, is that they’re difficult to control. “Our goal was making such bionic arms more intuitive, so that users could go about their tasks without having to think about it,” George says. To make this happen, his team came up with an AI bionic hand co-pilot.
Micro-management issues
Bionic hands’ control problems stem largely from their lack of autonomy. Grasping a paper cup without crushing it or catching a ball mid-flight appear so effortless because our natural movements rely on an elaborate system of reflexes and feedback loops. When an object you hold begins to slip, tiny mechanoreceptors in your fingertips send signals to the nervous system that make the hand tighten its grip. This all happens within 60 to 80 milliseconds—before you even consciously notice. This reflex is just one of many ways your brain automatically assists you in dexterity-based tasks.
A startup established three years ago to churn out a new class of high-power satellites has raised $250 million to ramp up production at its Southern California factory.
The company, named K2, announced the cash infusion on Thursday. K2’s Series C fundraising round was led by Redpoint Ventures, with additional funding from investment firms in the United States, the United Kingdom, and Germany. K2 has now raised more than $400 million since its founding in 2022 and is on track to launch its first major demonstration mission next year, officials said.
K2 aims to take advantage of a coming abundance of heavy- and super-heavy-lift launch capacity, with SpaceX’s Starship expected to begin deploying satellites as soon as next year. Blue Origin’s New Glenn rocket launched twice this year and will fly more in 2026 while engineers develop an even larger New Glenn with additional engines and more lift capability.
Scientists in Kansas believe Kernza could cut emissions, restore degraded soils and reshape the future of agriculture
On the concrete floor of a greenhouse in rural Kansas stands a neat grid of 100 plastic plant pots, each holding a straggly crown of strappy, grass-like leaves. These plants are perennials – they keep growing, year after year. That single characteristic separates them from soya beans, wheat, maize, rice and every other major grain crop, all of which are annuals: plants that live and die within a single growing season.
“These plants are the winners, the ones that get to pass their genes on [to future generations],” says Lee DeHaan of the Land Institute, an agricultural non-profit based in Salina, Kansas. If DeHaan’s breeding programme maintains its current progress, the descendant of these young perennial crop plants could one day usher in a wholesale revolution in agriculture.
Researchers found a chasm between the health reasons for which the public seeks out cannabis and what gold-standard science actually shows about its effectiveness.
Addiction experts, who studied hundreds of clinical trials, guidelines and surveys conducted over 15 years, found a gulf between how the public perceives cannabis and what gold-standard science shows.
Cadmium zinc telluride (CZT), a hard-to-manufacture semiconductor produced by only a handful of companies, is enabling a quiet revolution in medical imaging, science, and security by delivering faster scans, lower radiation doses, and far more precise X-ray and gamma-ray detection. "You get beautiful pictures from this scanner," says Dr Kshama Wechalekar, head of nuclear medicine and PET. "It's an amazing feat of engineering and physics." The BBC reports: Kromek is one of just a few firms in the world that can make CZT. You may never have heard of the stuff but, in Dr Wechalekar's words, it is enabling a "revolution" in medical imaging. This wonder material has many other uses, such as in X-ray telescopes, radiation detectors and airport security scanners. And it is increasingly sought-after. Investigations of patients' lungs performed by Dr Wechalekar and her colleagues involve looking for the presence of many tiny blood clots in people with long Covid, or a larger clot known as a pulmonary embolism, for example.
The 1-million-pound scanner works by detecting gamma rays emitted by a radioactive substance that is injected into patients' bodies. But the scanner's sensitivity means less of this substance is needed than before: "We can reduce doses about 30%," says Dr Wechalekar. While CZT-based scanners are not new in general, large, whole-body scanners such as this one are a relatively recent innovation. CZT itself has been around for decades but it is notoriously difficult to manufacture. "It has taken a long time for it to develop into an industrial-scale production process," says Arnab Basu, founding chief executive of Kromek.
[...] The newly formed CZT, a semiconductor, can detect tiny photon particles in X-rays and gamma rays with incredible precision -- like a highly specialized version of the light-sensing, silicon-based image sensor in your smartphone camera. Whenever a high energy photon strikes the CZT, it mobilizes an electron and this electrical signal can be used to make an image. Earlier scanner technology used a two-step process, which was not as precise. "It's digital," says Dr Basu. "It's a single conversion step. It retains all the important information such as timing, the energy of the X-ray that is hitting the CZT detector -- you can create color, or spectroscopic images."
Scientists say bears in southern Greenland differ genetically to those in the north, suggesting they could adjust
Changes in polar bear DNA that could help the animals adapt to warmer climates have been detected by researchers, in a study thought to be the first time a statistically significant link has been found between rising temperatures and changing DNA in a wild mammal species.
Climate breakdown is threatening the survival of polar bears. Two-thirds of them are expected to have disappeared by 2050 as their icy habitat melts and the weather becomes hotter.
The Centers for Disease Control and Prevention is in critical condition. This year, the premier public health agency had its funding brutally cut and staff gutted, its mission sabotaged, and its headquarters riddled with literal bullets. The over 500 rounds fired were meant for its scientists and public health experts, who endured only to be sidelined, ignored, and overruled by Health Secretary Robert F. Kennedy Jr., an anti-vaccine activist hellbent on warping the agency to fit his anti-science agenda.
Then, on August 27, Kennedy fired CDC Director Susan Monarez just weeks after she was confirmed by the Senate. She had refused to blindly approve vaccine recommendations from a panel of vaccine skeptics and contrarians that he had hand-selected. The agency descended into chaos, and Monarez wasn’t the only one to leave the agency that day.
Three top leaders had reached their breaking point and coordinated their resignations upon the dramatic ouster: Drs. Demetre Daskalakis, Debra Houry, and Daniel Jernigan walked out of the agency as their colleagues rallied around them.
Since the 1990s, physicists have pondered the tantalizing possibility of an exotic fourth type of neutrino, dubbed the “sterile” neutrino, that doesn’t interact with regular matter at all, apart from its fellow neutrinos, perhaps. But definitive experimental evidence for sterile neutrinos has remained elusive. Now it looks like the latest results from Fermilab’s MiniBooNE experiment have ruled out the sterile neutrino entirely, according to a paper published in the journal Nature.
How did the possibility of sterile neutrinos even become a thing? It all dates back to the so-called “solar neutrino problem.” Physicists detected the first solar neutrinos from the Sun in 1966. The only problem was that there were far fewer solar neutrinos being detected than predicted by theory, a conundrum that became known as the solar neutrino problem. In 1962, physicists discovered a second type (“flavor”) of neutrino, the muon neutrino. This was followed by the discovery of a third flavor, the tau neutrino, in 2000.
Physicists already suspected that neutrinos might be able to switch from one flavor to another. In 2002, scientists at the Sudbury Neutrino Observatory (or SNO) announced that they had solved the solar neutrino problem. The missing solar (electron) neutrinos were just in disguise, having changed into a different flavor on the long journey between the Sun and the Earth. If neutrinos oscillate, then they must have a teensy bit of mass after all. That posed another knotty neutrino-related problem. There are three neutrino flavors, but none of them has a well-defined mass. Rather, different kinds of “mass states” mix together in various ways to produce electron, muon, and tau neutrinos. That’s quantum weirdness for you.
It would be absurd to claim the UK has suddenly become a life-sciences leader thanks to the new pricing and tariffs pact
That’s gratitude, eh? It’s not even a fortnight since the government agreed to raise the prices the NHS pays for new medicines and here comes the boss of GSK, Britain’s second largest pharma firm, to extol the virtues of doing business in the US.
The US is “still the leading market in the world in terms of the launches of new drugs and vaccines”, said the chief executive, Emma Walmsley, in a BBC interview, explaining why GSK invests about three times as much over there as it does at home. Alongside China, the US is also “the best market in the world to do business development”.
NASA has lost contact with one of its three spacecraft orbiting Mars, the agency announced Tuesday. Meanwhile, a second Mars orbiter is perilously close to running out of fuel, and the third mission is running well past its warranty.
Ground teams last heard from the Mars Atmosphere and Volatile Evolution, or MAVEN, spacecraft on Saturday, December 6. “Telemetry from MAVEN had showed all subsystems working normally before it orbited behind the red planet,” NASA said in a short statement. “After the spacecraft emerged from behind Mars, NASA’s Deep Space Network did not observe a signal.”
NASA said mission controllers are “investigating the anomaly to address the situation. More information will be shared once it becomes available.”
Space agency is investigating after Maven abruptly stopped communicating to ground stations over the weekend
Nasa has lost contact with a spacecraft that has orbited Mars for more than a decade, though the US space agency said it was trying to re-establish a communications link.
Maven abruptly stopped communicating to ground stations over the weekend. Nasa said this week that the spacecraft had been working fine before it went behind the red planet. When it reappeared, there was only silence. “Telemetry showed all subsystems working normally before it orbited behind [Mars],” Nasa said in a statement.
An NHS leader who said people with flu symptoms “must wear” a face mask in public risks causing “confusion” among the public over official guidance on how to fight the virus, health experts have warned.
The number of people in hospital with flu in England is at a record level for this time of year. At least six hospitals across the UK have told patients to stay away due to a surge in flu cases sweeping the country this week.
A fin whale washed ashore in Anchorage and was left there for months. Then a self-described ‘wacko’ museum director made a plan
When a whale dies, its body descends to the bottom of the deep sea in a transformative phenomenon called a whale fall. A whale’s death jump-starts an explosion of life, enough to feed and sustain a deep-ocean ecosystem for decades.
There are a lot of ways whales can die. Migrating whales lose their way and, unable to find their way back from unfamiliar waters, are stranded. They can starve when prey disappears or fall to predators such as orcas. They become bycatch, tangled in fishing lines and nets. Mass whale deaths have been linked to marine heatwaves and the toxic algae blooms that follow.
Groundbreaking find makes compelling case that humans were lighting fires much earlier than originally believed
Humans mastered the art of creating fire 400,000 years ago, almost 350,000 years earlier than previously known, according to a groundbreaking discovery in a field in Suffolk.
It is known that humans used natural fire more than 1m years ago, but until now the earliest unambiguous example of humans lighting fires came from a site in northern France dating from 50,000 years ago.
Heat-reddened clay, fire-cracked stone, and fragments of pyrite mark where Neanderthals gathered around a campfire 400,000 years ago in what’s now Suffolk, England.
Based on chemical analysis of the sediment at the site, along with the telltale presence of pyrite, a mineral not naturally found nearby but very handy for striking sparks with flint, British Museum archaeologist Rob Davis and his colleagues say the Neanderthals probably started the fire themselves. That makes the abandoned English clay pit at Barnham the oldest evidence in the world that people (Neanderthal people, in this case) had learned to not only use fire, but also create it and control it.
A cozy Neanderthal campfire
Today, the Barnham site is part of an abandoned clay pit where workers first discovered stone tools in the early 1900s. But 400,000 years ago, it would have been a picturesque little spot at the edge of a stream-fed pond, surrounded by a mix of forest and grassland. There are no hominin fossils here, but archaeologists unearthed a Neanderthal skull about 100 kilometers to the south, so the hominins at Barnham were probably also Neanderthals. The place would have offered a group of Neanderthals a relatively quiet, sheltered place to set up camp, according to Davis and his colleagues.
As three immigrants claim Nobel Prizes in science for the United States this year, experts warn that immigration crackdowns could undo American innovation.
As three immigrants claim Nobel Prizes in science for the United States this year, experts warn that immigration crackdowns could undo American innovation.
Scientists issue urgent warning about chemicals, found to cause cancer and infertility as well as harming environment
Scientists have issued an urgent warning that some of the synthetic chemicals that help underpin the current food system are driving increased rates of cancer, neurodevelopmental conditions and infertility, while degrading the foundations of global agriculture.
The health burden from phthalates, bisphenols, pesticides and Pfas “forever chemicals” amounts to up to $2.2tn a year – roughly as much as the profits of the world’s 100 largest publicly listed companies, according to the report published on Wednesday.
Human beings in 7th place out of 35 species on monogamy scale, according to a study by Cambridge University
Humans are playing in the premier league of monogamous mammals, according to a new ranking of animals by their reproductive habits, but we may need a new manager to beat the beavers.
In the study from University of Cambridge, humans ranked 7th out of 35 species on the monogamy scale, pipping white-handed gibbons and meerkats, but lagging behind moustached tamarins and Eurasian beavers.
Conservationist who devoted his life to the study and preservation of the African elephant
The British scientist Iain Douglas-Hamilton, who has died aged 83, became the world’s leading authority on the behaviour of African elephants and played a vital part in ensuring their conservation.
His efforts to save the African elephant began in 1965 when, as an Oxford zoology graduate who had also just received his pilot’s licence, he flew his Piper Pacer bush plane from Nairobi down to Tanzania’s pocket-sized Lake Manyara national park. The challenge he had accepted at the age of 23 was how to solve the problem of 450 elephants confined in a space too small to support them.
On Monday, US District Court Judge Patti Saris vacated a Trump executive order that brought a halt to all offshore wind power development, as well as some projects on land. That order had called for the suspension of all permitting for wind power on federal land and waters pending a review of current practices. This led states and an organization representing wind power companies to sue, claiming among other things that the suspension was arbitrary and capricious.
Over 10 months since the relevant government agencies were ordered to start a re-evaluation of the permitting process, testimony revealed that they had barely begun to develop the concept of a review. As such, the only reason they could offer in defense of the suspension consisted of Trump’s executive order and a Department of the Interior memo implementing it. “Whatever level of explanation is required when deviating from longstanding agency practice,” Judge Saris wrote, “this is not it.”
Lifting Trump’s suspension does not require the immediate approval of any wind projects. Instead, the relevant agencies are likely to continue following Trump’s wishes and slow-walking any leasing and licensing processes, which may force states and project owners to sue individually. But it does provide a legal backdrop for any suits that ultimately occur, one in which the government’s actions have little justification beyond Trump’s personal animosity toward wind power.
Despite claims of environmental leadership and promises to preserve the Amazon rainforest ahead of COP30, Brazil is stripping away protections for the region’s vital ecosystems faster than workers dismantled the tents that housed the recent global climate summit in Belém.
On Nov. 27, less than a week after COP30 ended, a powerful political bloc in Brazil’s National Congress, representing agribusiness, and development interests, weakened safeguards for the Amazon’s rivers, forests, and Indigenous communities.
The rollback centered on provisions in an environmental licensing bill passed by the government a few months before COP30. The law began to take shape well before, during the Jair Bolsonaro presidency from 2019 to 2023. It reflected the deregulatory agenda of the rural caucus, the Frente Parlamentar da Agropecuária, which wielded significant power during his term and remains influential today.
Back in 2023, we reported on MIT scientists’ conclusion that the ancient Romans employed “hot mixing” with quicklime, among other strategies, to make their famous concrete, giving the material self-healing functionality. The only snag was that this didn’t match the recipe as described in historical texts. Now the same team is back with a fresh analysis of samples collected from a recently discovered site that confirms the Romans did indeed use hot mixing, according to a new paper published in the journal Nature Communications.
As we’ve reported previously, like today’s Portland cement (a basic ingredient of modern concrete), ancient Roman concrete was basically a mix of a semi-liquid mortar and aggregate. Portland cement is typically made by heating limestone and clay (as well as sandstone, ash, chalk, and iron) in a kiln. The resulting clinker is then ground into a fine powder with just a touch of added gypsum to achieve a smooth, flat surface. But the aggregate used to make Roman concrete was made up of fist-sized pieces of stone or bricks.
In his treatise De architectura (circa 30 CE), the Roman architect and engineer Vitruvius wrote about how to build concrete walls for funerary structures that could endure for a long time without falling into ruin. He recommended the walls be at least two feet thick, made of either “squared red stone or of brick or lava laid in courses.” The brick or volcanic rock aggregate should be bound with mortar composed of hydrated lime and porous fragments of glass and crystals from volcanic eruptions (known as volcanic tephra).
There are apparently breakthroughs on the way for those with sleep disorders – which sent me down a rabbit hole of research...
I met a guy in pharmaceuticals who told me about a bunch of cool breakthroughs in sleep meds: mainly, we may be on the brink of a new Wegovy, but in this case it’s a drug to cure narcolepsy. I suggested the two things are not quite the same, given that obesity is a global epidemic and narcolepsy is fairly rare. He countered that the way the drug works might also have applications for insomnia; similar to the Post-it note having been invented by someone trying to create the world’s strongest glue.
Anyway, in the course of this, I discovered the test for type 1 narcolepsy, which is that you’re put in a room with zero stimulation – nothing to read, no one to chat to, perfect silence, perfect temperature – and timed on how long it takes you to fall asleep. If it’s under eight minutes, you’re narcoleptic. But the average, for a person with no complaints in that area at all, is 22 minutes. I was completely incredulous. This is a grip on consciousness more or less the same as a house cat. Bored? Go to sleep. Even a dog will have a quick look for something to eat first.
Popular genetics tests can’t tell you much about your dog’s personality, according to a recent study.
A team of geneticists recently found no connection between simple genetic variants and behavioral traits in more than 3,200 dogs, even though previous studies suggested that hundreds of genes might predict aspects of a dog’s behavior and personality. That’s despite the popularity of at-home genetic tests that claim they can tell you whether your dog’s genes contain the recipe for anxiety or a fondness for cuddles.
This is Max, and no single genetic variant can explain why he is the way he is.
Credit:
Kiona Smith
Gattaca for dogs, except it doesn’t work
University of Massachusetts genomicist Kathryn Lord and her colleagues compared DNA sequences and behavioral surveys from more than 3,000 dogs whose humans had enrolled them in the Darwin’s Ark project (and filled out the surveys). “Genetic tests for behavioral and personality traits in dogs are now being marketed to pet owners, but their predictive accuracy has not been validated,” wrote Lord and her colleagues in their recent paper.
CHANCAY, Peru—The elevator doors leading to the fifth-floor control center open like stage curtains onto a theater-sized screen.
This “Operations Productivity Dashboard” instantaneously displays a battery of data: vehicle locations, shipping times, entry times, loading data, unloading data, efficiency statistics.
Most striking, though, are the bold lines arcing over the dashboard’s deep-blue Pacific—digital streaks illustrating the routes that lead thousands of miles across the ocean, from this unassuming city, to Asia’s biggest ports.
alternative_right shares a report from ScienceAlert: Engineers at Cornell University have created the blackest fabric on record, finding it absorbs 99.87 percent of all light that dares to illuminate its surface. [...] In this case, the Cornell researchers dyed a white merino wool knit fabric with a synthetic melanin polymer called polydopamine. Then, they placed the material in a plasma chamber, and etched structures called nanofibrils -- essentially, tiny fibers that trap light. "The light basically bounces back and forth between the fibrils, instead of reflecting back out -- that's what creates the ultrablack effect," says Hansadi Jayamaha, fiber scientist and designer at Cornell.
The structure was inspired by the magnificent riflebird (Ptiloris magnificus). Hailing from New Guinea and northern Australia, male riflebirds are known for their iridescent blue-green chests contrasted with ultrablack feathers elsewhere on their bodies. The Cornell material actually outperforms the bird's natural ultrablackness in some ways. The bird is blackest when viewed straight on, but becomes reflective from an angle. The material, on the other hand, retains its light absorption powers when viewed from up to 60 degrees either side. The findings have been published in the journal Nature Communications.
The Black Death ravaged medieval Western Europe, ultimately wiping out roughly one-third of the population. Scientists have identified the bacterium responsible and its likely origins, but certain specifics of how and why it spread to Europe are less clear. According to a new paper published in the journal Communications Earth & Environment, either one large volcanic eruption or a cluster of eruptions might have been the triggering factor, setting off a chain of events that brought the plague to the Mediterranean region in the 1340s.
Technically, we’re talking about the second plague pandemic. The first, known as the Justinian Plague, broke out about 541 CE and quickly spread across Asia, North Africa, the Middle East, and Europe. (The Eastern Roman Emperor Justinian I, for whom the pandemic is named, actually survived the disease.) There continued to be outbreaks of the plague over the next 300 years, although the disease gradually became less virulent and died out. Or so it seemed.
In the Middle Ages, the Black Death burst onto the scene, with the first historically documented outbreak occurring in 1346 in the Lower Volga and Black Sea regions. That was just the beginning of the second pandemic. During the 1630s, fresh outbreaks of plague killed half the populations of affected cities. Another bout of the plague significantly culled the population of France during an outbreak between 1647 and 1649, followed by an epidemic in London in the summer of 1665. The latter was so virulent that, by October, one in 10 Londoners had succumbed to the disease—over 60,000 people. Similar numbers perished in an outbreak in Holland in the 1660s. The pandemic had run its course by the early 19th century, but a third plague pandemic hit China and India in the 1890s. There are still occasional outbreaks today.
As global warming accelerates, about 480 million people in North Africa and the Arabian Peninsula face intensifying and in some places unsurvivable heat, as well as drought, famine, and the risk of mass displacement, the World Meteorological Organization warned Thursday.
The 22 Arab region countries covered in the WMO’s new State of the Climate report produce about a quarter of the world’s oil, yet directly account for only 5 to 7 percent of global greenhouse gas emissions from their own territories. The climate paradox positions the region as both a linchpin of the global fossil-fuel economy and one of the most vulnerable geographic areas.
WMO Secretary-General Celeste Saulo said extreme heat is pushing communities in the region to their physical limits. Droughts show no sign of letting up in one of the world’s most water-stressed regions, but at the same time, parts of it have been devastated by record rains and flooding, she added.
Welcome to Edition 8.21 of the Rocket Report! We’re back after the Thanksgiving holiday with more launch news. Most of the big stories over the last couple of weeks came from abroad. Russian rockets and launch pads didn’t fare so well. China’s launch industry celebrated several key missions. SpaceX was busy, too, with seven launches over the last two weeks, six of them carrying more Starlink Internet satellites into orbit. We expect between 15 and 20 more orbital launch attempts worldwide before the end of the year.
As always, we welcome reader submissions. If you don’t want to miss an issue, please subscribe using the box below (the form will not appear on AMP-enabled versions of the site). Each report will include information on small-, medium-, and heavy-lift rockets, as well as a quick look ahead at the next three launches on the calendar.
Another Sarmat failure. A Russian intercontinental ballistic missile (ICBM) fired from an underground silo on the country’s southern steppe on November 28 on a scheduled test to deliver a dummy warhead to a remote impact zone nearly 4,000 miles away. The missile didn’t even make it 4,000 feet, Ars reports. Russia’s military has been silent on the accident, but the missile’s crash was seen and heard for miles around the Dombarovsky air base in Orenburg Oblast near the Russian-Kazakh border. A video posted by the Russian blog site MilitaryRussia.ru on Telegram and widely shared on other social media platforms showed the missile veering off course immediately after launch before cartwheeling upside down, losing power, and then crashing a short distance from the launch site.
Roughly two years ago, Sam Altman tweeted that AI systems would be capable of superhuman persuasion well before achieving general intelligence—a prediction that raised concerns about the influence AI could have over democratic elections.
To see if conversational large language models can really sway political views of the public, scientists at the UK AI Security Institute, MIT, Stanford, Carnegie Mellon, and many other institutions performed by far the largest study on AI persuasiveness to date, involving nearly 80,000 participants in the UK. It turned out political AI chatbots fell far short of superhuman persuasiveness, but the study raises some more nuanced issues about our interactions with AI.
AI dystopias
The public debate about the impact AI has on politics has largely revolved around notions drawn from dystopian sci-fi. Large language models have access to essentially every fact and story ever published about any issue or candidate. They have processed information from books on psychology, negotiations, and human manipulation. They can rely on absurdly high computing power in huge data centers worldwide. On top of that, they can often access tons of personal information about individual users thanks to hundreds upon hundreds of online interactions at their disposal.
Necrobotics is a field of engineering that builds robots out of a mix of synthetic materials and animal body parts. It has produced micro-grippers with pneumatically operated legs taken from dead spiders and walking robots based on deceased cockroaches. “These necrobotics papers inspired us to build something different,” said Changhong Cao, a mechanical engineering professor at the McGill University in Montreal, Canada.
Cao’s team didn’t go for a robot—instead, it adapted a female mosquito proboscis to work as a nozzle in a super-precise 3D printer. And it worked surprisingly well.
Fangs and stings
To find the right nozzle for their 3D necroprinting system, Cao’s team began with a broad survey of natural micro-dispensing tips. The researchers examined stingers of bees, wasps, and scorpions; the fangs of venomous snakes; and the claws of centipedes. All of those evolved to deliver a fluid to the target, which is roughly what a 3D printer’s nozzle does. But they all had issues. “Some were too curved and curved for high-precision 3D printing,” Cao explained. “Also, they were optimized for delivering pulses of venom, not for a steady, continuous flow, which is what you need for printing.”
Just a tiny amount of fentanyl, the equivalent of a few grains of sand, is enough to stop a person’s breathing. The synthetic opioid is tasteless, odorless, and invisible when mixed with other substances, and drug users are often unaware of its presence.
It’s why biotech entrepreneur Collin Gage is aiming to protect people against the drug’s lethal effects. In 2023, he became the cofounder and CEO of ARMR Sciences to develop a vaccine against fentanyl. Now, the company is launching a trial to test its vaccine in people for the first time. The goal: prevent deaths from overdose.
“It became very apparent to me that as I assessed the treatment landscape, everything that exists is reactionary,” Gage says. “I thought, why are we not preventing this?”
On Friday, Vinay Prasad—the Food and Drug Administration’s chief medical and scientific officer and its top vaccine regulator—emailed a stunning memo to staff that quickly leaked to the press. Without evidence, Prasad claimed COVID-19 vaccines have killed 10 children in the US, and, as such, he announced unilateral, sweeping changes to the way the agency regulates and approves vaccines, including seasonal flu shots.
On Wednesday evening, a dozen former FDA commissioners, who collectively oversaw the agency for more than 35 years, responded to the memo with a scathing rebuke. Uniting to publish their response in the New England Journal of Medicine, the former commissioners said they were “deeply concerned” by Prasad’s memo, which they framed as a “threat” to the FDA’s work and a danger to Americans’ health.
In his memo, Prasad called for abandoning the FDA’s current framework for updating seasonal flu shots and other vaccines, such as those for COVID-19. Those updates currently involve studies that measure well-characterized immune responses (called immunobridging studies). Prasad dismissed this approach as insufficient and, instead, plans to require expensive randomized trials, which can take months to years for each vaccine update.
The fossil and genetic evidence agree that modern humans originated in Africa. The most genetically diverse human populations—the groups that have had the longest time to pick up novel mutations—live there today. But the history of what went on within Africa between our origins and the present day is a bit murky.
That’s partly because DNA doesn’t survive long in the conditions typical of most of the continent, which has largely limited us to trying to reconstruct the past using data from present-day populations. The other part is that many of those present-day populations have been impacted by the vast genetic churn caused by the Bantu expansion, which left its traces across most of the populations south of the Sahara.
But a new study has managed to extract genomes from ancient samples in southern Africa. While all of these are relatively recent, dating from after the end of the most recent glacial period, they reveal a distinct southern African population that was relatively large, outside of the range of previously described human variation, and it remained isolated until only about 1,000 years ago.
The US Department of Energy has approved an $8.6 million grant that will allow the nation’s first utility-led geothermal heating and cooling network to double in size.
Gas and electric utility Eversource Energy completed the first phase of its geothermal network in Framingham, Massachusetts, in 2024. Eversource is a co-recipient of the award along with the city of Framingham and HEET, a Boston-based nonprofit that focuses on geothermal energy and is the lead recipient of the funding.
Geothermal networks are widely considered among the most energy-efficient ways to heat and cool buildings. The federal money will allow Eversource to add approximately 140 new customers to the Framingham network and fund research to monitor the system’s performance.
The president withdrew Jared Isaacman’s nomination to lead the space agency in June, but senators of both parties appeared willing to give him a second shot at confirmation.
China’s first attempt to land an orbital-class rocket may have ended in a fiery crash, but the company responsible for the mission had a lot to celebrate with the first flight of its new methane-fueled launcher.
LandSpace, a decade-old company based in Beijing, launched its new Zhuque-3 rocket for the first time at 11 pm EST Tuesday (04:0 UTC Wednesday), or noon local time at the Jiuquan launch site in northwestern China.
Powered by nine methane-fueled engines, the Zhuque-3 (Vermillion Bird-3) rocket climbed away from its launch pad with more than 1.7 million pounds of thrust. The 216-foot-tall (66-meter) launcher headed southeast, soaring through clear skies before releasing its first stage booster about two minutes into the flight.
On Wednesday, three NASA astronomers released an analysis showing that several planned orbital telescopes would see their images criss-crossed by planned satellite constellations, such as a fully expanded Starlink and its competitors. While the impact of these constellations on ground-based has been widely considered, orbital hardware was thought to be relatively immune from their interference. But the planned expansion of constellations, coupled with some of the features of upcoming missions, will mean that at least one proposed observatory will see an average of nearly 100 satellite tracks in every exposure.
Making matters worse, some of the planned measures meant to minimize the impact on ground-based telescopes will make things worse for those in orbit.
Constellations vs. astronomy
Satellite constellations are a relatively new threat to astronomy; prior to the drop in launch costs driven by SpaceX’s reusable rockets, the largest constellations in orbit consisted of a few dozen satellites. But the rapid growth of the Starlink system caused problems for ground-based astronomy that are not easy to solve.
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