About a month ago, a Chinese rocket took off from a remote spaceport in the Gobi Desert, released 10 satellites into orbit, then reignited its engine and put itself on a trajectory to rain down debris over the American Midwest.

The rocket's flight on September 15 lasted between 75 and 80 minutes, and it came down without completing a full orbit of the Earth. Social media posts at the time showed streaks of fiery debris falling from the sky, heading north over Kansas toward Minnesota. The overnight spectacle was also visible on the western horizon from Wisconsin.

The exact time, location, and direction of the debris allowed experts to connect it to the launch of a Zhuque-2E rocket, a medium-lift vehicle built by a Chinese company called LandSpace. The rocket had launched from Dongfeng, a commercial launch zone co-located with the military-run Jiuquan Satellite Launch Center in northwestern China, less than two hours before.

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Antibody patterns in the blood may help doctors identify people at risk so they can be treated earlier, research shows

Patterns of antibodies in people’s blood could predict the onset of inflammatory bowel disease (IBD) a decade before diagnosis, according to research that raises hopes for catching the condition early.

Crohn’s disease and ulcerative colitis, the two main forms of IBD, are typically treated only after symptoms appear, when the gut has already been damaged. But scientists found that the immune system sends warning signals up to a decade before diagnosis, paving the way for potentially earlier detection and even prevention.

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© Photograph: Teodor Lazarev/Alamy

© Photograph: Teodor Lazarev/Alamy

In the three weeks since a health worker’s death in Siberia, officials have stonewalled the WHO – setting a worrying precedent for future pandemics

Is there a plague outbreak in Russia? If the answer were a clear yes, there shouldn’t be much reason to worry. With swift medical intervention, plague is treatable. But in the nearly three weeks since a worker at a Siberian plague research unit died of a mysterious respiratory illness, state officials have been consistently tight-lipped about what happened and whether there were any further cases.

It is this uncertainty that has the World Health Organization (WHO) and international community worried: partly because there is a – very small – risk of an outbreak, and partly because it is yet another warning that the international coordination we rely on to prevent pandemics is fraying along with the rest of international politics, and could easily fail to protect us in the future.

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© Photograph: Smirnov Vladimir/Anadolu/Getty Images

© Photograph: Smirnov Vladimir/Anadolu/Getty Images

Iboga root, central to several Gabonese ritual traditions, is believed to have huge potential for use in treating addiction and some mental illnesses

The temple is dark, its sandy floor edged with candles. People sit shoulder to shoulder beneath palm fronds hung from the rafters. Through the night, they swallow what they have come here for: a bitter root bark called iboga.

Tabernanthe iboga is a slow-growing central African rainforest shrub, the root bark of which has long been used in several Gabonese ritual traditions.

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© Photograph: Jorge Fernández/LightRocket/Getty Images

© Photograph: Jorge Fernández/LightRocket/Getty Images

© Photograph: Jorge Fernández/LightRocket/Getty Images

Japanese space agency leading five-year mission to Phobos, one of ‘most important unclimbed mountains in the solar system’

Japan is to launch a spacecraft on the world’s first mission to bring back samples from Phobos, one of the two small, potato-shaped moons orbiting Mars.

Scientists hope the mission, which is expected to take five years, will provide clues to how Phobos and its smaller sibling Deimos formed, and hopefully even shed light on the origins of life in the solar system.

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© Photograph: NASA/AP

© Photograph: NASA/AP

© Photograph: NASA/AP

As the planet warms, airlines are grappling with what this means for air travel – and for the passengers who simply refuse to keep their seatbelts fastened

It was a swelteringly hot afternoon in south-west Myanmar on 21 May 2024. Tropical thunderstorms, showers and highs of 36C were forecast for the area around the Irrawaddy Basin. High above, monsoonal heat and humidity were building into a vast convective column of water vapour, a towering cumulonimbus cloud soaring up to 35,000ft (more than 10,500 metres) into the air. From the ground, it would have looked like something from a children’s picture book – a soft, fluffy white mass. But for Singapore Airlines flight SQ321 passing just above, it was anything but benign.

In the cabin of the Boeing 777, passengers were being woken up for breakfast with three hours to go on the journey from London to Singapore. For the 210 travellers on board, the past 10 hours had been uneventful. The seatbelt signs were off. Some were milling around, others were using the toilets, and cabin staff were preparing trolleys for service. At 2.19pm and 23 seconds local time, moderate turbulence shook the plane for 17 seconds and the seatbelt sign was switched on. Then, as one passenger described it, it was “like a grenade had gone off”. In just 4.6 seconds, any passenger not strapped in hit the roof with 1.5 times the force of gravity and was thrown back on the floor in an instant.

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© Illustration: Guardian Design

© Illustration: Guardian Design

© Illustration: Guardian Design

Close to 1 billion meetings take place each day around the world. CEOs spend nearly three-quarters of their workdays in meetings. Planning for and spearheading meetings eats up the lion’s share of managers’ time. In much of the industrialized world, meetings are both the metronomes and menaces of people’s working lives.

Given the enormous time spent in workplace meetings, do we know what they accomplish or how to make them as worthwhile as possible? For decades, the answer was… not really. Meetings weren’t a particularly accessible subject of study. But that has changed. Once a tiny niche area, “meeting science” is a growing specialization among organizational and social psychologists. The field is accelerating as archived virtual meetings provide vast swaths of data. And it is providing a fascinating window into human behavior.

Meeting to talk helps fulfill basic human needs to connect, communicate, and cooperate. People have long come together—in caves, fields, market squares, and town halls—to get something done, share ideas, get on the same page, or just to remark on the weather. But meeting scientists define their subject as gatherings of people “with some goal or structure to the event,” says organizational psychologist Liana Kreamer of the Florida Institute of Technology, who coauthored a review of over three decades of meeting science in the 2026 Annual Review of Organizational Psychology and Organizational Behavior.

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The Tesla Roadster 2 drove up a curved ramp before using SpaceX rocket thrusters to fly, flip and land

Elon Musk has revealed Tesla’s latest model, which he claims will be the world’s first flying car, using technology from his aerospace company SpaceX to “basically fly like a rocket”.

The billionaire, who hosted a demonstration of the Tesla Roadster 2 at the SpaceX rocket development and testing facility in Texas, said the sports car could go from 0 to 60mph in a record time of less than a second and had thrusters.

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© Photograph: Tesla/AFP/Getty Images

© Photograph: Tesla/AFP/Getty Images

© Photograph: Tesla/AFP/Getty Images

Timekeepers have officially voted to eliminate the leap second, allowing Coordinated Universal Time to drift as much as one hour from Earth's rotation before a correction is needed. The change ends decades of occasionally adding or subtracting seconds and replaces it with a hypothetical "leap hour" that likely wouldn't be necessary for hundreds or even thousands of years. Smithsonian Magazine reports: "It's kind of a philosophical discussion, because if a leap hour happens, it won't be for a very, very long time," Christian Bizouard, director of the IERS Earth Orientation Center in France, tells the Guardian's Ian Sample. "What we are doing is pushing back the decision." The move caps off 30 years of debate, as the leap second has been highly controversial in the world of timekeeping. Leap seconds aren't nearly as smooth of a fix as leap years are, and they can cause computer and website issues. Reddit famously crashed when a leap second was added on June 30, 2012. It's "always been a problem," Judah Levine, a former researcher at the NIST's Time and Frequency Division, tells Scientific American's Emma Gometz. Instead of adding the entire second all at once, companies such as Google and Meta add the extra time in smaller segments in a tactic called "smearing," according to the Conversation. It's not a simple task, however, and companies that employ smearing have long lobbied to get rid of the leap second. What's more, with Earth's recent spin acceleration, timekeepers around the world were facing the possibility of the world's first negative leap second, in which a second would be subtracted from UTC. This sparked fears, akin to those surrounding Y2K, that our modern technologies wouldn't be able to handle such a change. "It's never happened before, and therefore the software for that has never been tested," Darryl Veitch, a researcher who leads the Timing Lab at the University of Technology Sydney, tells the Australian Broadcasting Corporation's Ellen Phiddian. But others argued that it wouldn't be much of a problem. The vote means that in the future, UTC will be allowed to diverge from astronomical time more than ever before.

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How architects worked with harsh environment to create sustainable building in location where fossils were found

Viewed from afar, the silver-hued Hami Pterosaur Museum almost looks like a space base on Mars. Viewed from above, it resembles a collection of dinosaur eggs in the sand. Nestled in the Gobi desert, in north-west China, the new tourist attraction showcases hundreds of impressive fossils of pterosaurs, ancient flying reptiles related to dinosaurs. But far from reflecting its prehistoric exhibits, the building itself is a modern-day architectural specimen.

Designed with underground exhibition halls, giant light funnels and sprawling solar farms, the museum is able to operate sustainably while withstanding an extremely harsh environment.

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© Photograph: Turenscape

© Photograph: Turenscape

© Photograph: Turenscape

The remains of Edward Lelburian Jackson were first discovered in 2022, and an initial autopsy revealed he was killed decades ago

After four years, a piece of the haunting mystery uncovered in the waning waters of drought-stricken Lake Mead has been solved.

Since the remains of an unknown homicide victim were discovered stuffed inside a barrel in 2022, Las Vegas investigators have been searching not for his killer – but for his identity. At a press conference on Thursday, Clark county coroner Melanie Rouse shared his name publicly for the first time: Edward Lelburian Jackson.

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© Photograph: John Locher/AP

© Photograph: John Locher/AP

© Photograph: John Locher/AP

The Liberty Bell, with its famous crack, hasn't been rung in 180 years, but that hasn't stopped scientists from pondering what the bell might have sounded like when tolling. In honor of the nation's 250th anniversary, researchers at Penn State University have modeled its acoustic properties, drawing on data collected from one of the bell's replicas. The work was first presented at a meeting of the Acoustical Society of America in Philadelphia earlier this year, followed by an article in Physics Today.

Historians aren't sure exactly when the Liberty Bell acquired its distinctive crack, just that it occurred sometime between 1817 and 1846. An 1846 account in the Public Ledger described the ringing of the bell on February 23 that year and mentioned that the bell had developed a crack, which someone had attempted to fix by filing the sides down. But it didn't work: The February 23 ringing extended the crack even more, so much so that "the old Independence Bell ... now hangs in the great steeple irreparably cracked and forever dumb." Nobody has heard it ring since.

This wasn't the first time the bell had cracked; the rim cracked shortly after it arrived in Philadelphia in 1752, the first time the clapper struck while testing the sound. It was recast by two local foundry workers, John Pass and John Stow, not once but twice, because the first recast produced a sound that one bystander likened to coal scuttles banging together.

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One reason plastics are used so often is that they’re chemically inert, meaning bags, food containers, and cups don't react with what we put in them. Yet they can still break down into microplastics, which turn up in drinking water, human blood, arteries, and brains. The consequences of that are uncertain.

“Whether microplastics can directly cause human disease is still being researched,” said Wei Min, a chemist at Columbia University. In a new Nature study, Min's team took a step toward answering this question by demonstrating that microplastics are likely not as chemically inert as we might expect.

Microdroplet chemistry

Min's lab has spent years working on microdroplet chemistry, studying how water broken into tiny droplets behaves at its boundary with air. These droplets have been reported to generate reactive oxygen species, or ROS, a family of harmful, oxygen-containing molecules. “ROS will essentially bump into proteins, lipids, DNA, and cause damage,” Min said. “You could break a DNA strand into segments. You could mutate DNA; you could misfold proteins.”

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Rocket Lab announced Wednesday that its Neutron launch vehicle won't fly until 2027, citing an issue discovered during manufacturing of the rocket's carbon composite structures.

The announcement was public confirmation of what nearly everyone inside Rocket Lab and the wider space industry already knew. The most recent official update from Rocket Lab in August suggested the company still held hope of delivering the first Neutron rocket to its launch pad at Wallops Island, Virginia, before the end of this year, a schedule that would have almost certainly pushed the first flight into 2027.

But Rocket Lab's statement Wednesday about Neutron's schedule suggests the company is still struggling with manufacturing the rocket's large booster stage. Neutron's reusable first stage is made of carbon composite structures, which offer low weight, high strength, and corrosion resistance. But carbon composites in aerospace are generally harder to manufacture than metallic structures.

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© Rocket Lab

Coral-fringed tropical atolls are among the landforms most threatened by global warming, but many have a potential superpower: Healthy ecosystems may help them keep pace with rising seas.

Atoll islands with native vegetation and thriving seabird populations are “naturally active systems that can change and adapt to their environmental conditions if they are allowed to do so,” said Nick Graham, a marine ecologist at Lancaster University in the United Kingdom, who led an international team of scientists that studied island resilience across 28 atoll islands in the Pacific and Indian oceans.

Their paper, published Wednesday in Science Advances, shows that restoring atoll ecosystems reinforces their growth. Seabirds ferry nutrients from the open ocean and deposit them on the atolls as guano that nurtures land plants, marine life and coral growth. This provides more material for reef building, as parrotfish and other reef feeders turn dead coral into sand to maintain beaches, while native plants with extensive root networks stabilize sediments.

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International delegates agree leap second no longer tenable, but first leap hour not likely to happen for thousands of years

After decades of discussion, quibbling and worrying about clocks in computer systems, the world’s official timekeepers have voted to replace what many viewed as a tiresome correction: the leap second. It’s time, they say, for the leap hour.

Delegates from 69 countries cast their votes on Thursday at a conference in France of the International Bureau of Weights and Measures, which ensures the world sticks to the same standards of time, weight, distance and more.

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© Photograph: coward_lion/Getty Images

© Photograph: coward_lion/Getty Images

Adult excavated in an Iraqi Kurdistan cave died more than 70,000 years ago and bears ‘kill shot’ shoulder wound

A smooth round hole in the shoulder blade of a Neanderthal who died more than 70,000 years ago may be the oldest evidence so far of a human ancestor being killed by a wooden spear.

Archaeologists spotted the distinctive injury after excavating skeletal remains of the adult and other Neanderthals from under nearly 8 metres of rock and sediment in the Shanidar cave in Iraqi Kurdistan.

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© Photograph: University of Cambridge

© Photograph: University of Cambridge

© Photograph: University of Cambridge

Workers have always been monitored by their bosses, first through output targets, and then via computer software labelled ‘bossware’. But AI is transforming the capabilities of these systems, processing huge volumes of data to provide minute-by-minute accounts of activity, and productivity. To find out more, Ian Sample hears from UK technology editor Robert Booth. He explains which sectors are adopting this approach, why they are doing it, and how it could end up being counterproductive.

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© Photograph: Alamy

© Photograph: Alamy

© Photograph: Alamy

Downe, Kent: It’s hard not to feel the earth move by a visit to the great man’s house. He truly valued these creatures of the dirt

The garden beds are moistened by steady rain, but the ground is still unyielding. A blackbird hops across bare soil. A dart, a jab, and up it comes – a wriggling tube of pink flesh. A simple catch. But when I rummage in the dirt, my only reward is loam under the fingernails. Perhaps I should have brought a bassoon.

I’ve come to Down House. Here, Charles Darwin changed the world. And here he wrote his last book, its title usually shortened for convenience: Earthworms.

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© Photograph: blickwinkel/Alamy

© Photograph: blickwinkel/Alamy

© Photograph: blickwinkel/Alamy

Workers have always been monitored by their bosses, first through output targets, and then via computer software labelled ‘bossware’. But AI is transforming the capabilities of these systems, processing huge volumes of data to provide minute-by-minute accounts of activity, and productivity. To find out more, Ian Sample hears from UK technology editor Robert Booth. He explains which sectors are adopting this approach, why they are doing it, and how it could end up being counterproductive.

Teachers at Euan Blair firm report ‘horrendous stress’ after AI used to rate their work

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© Photograph: Aleksandr Davydov/Alamy

© Photograph: Aleksandr Davydov/Alamy

© Photograph: Aleksandr Davydov/Alamy

Most planetary scientists will tell you the heyday of Venus exploration was more than a generation ago. That is about to change.

Two NASA missions are on track to launch to Venus in the early 2030s. The first, known as the Deep Atmosphere Venus Investigation of Noble gases, Chemistry, and Imaging (DAVINCI), is now scheduled for launch in December 2030, a year earlier than previously planned. DAVINCI will send a parachute-assisted descent probe through the atmosphere of Venus, returning the first direct images of the planet's surface since 1982. A second mission, Venus Emissivity, Radio science, InSAR, Topography, And Spectroscopy (VERITAS), will follow with a launch in November 2032 to map the Venusian surface by radar from orbit.

The European Space Agency is building another orbiter, Envision, for launch to Venus in 2032. The Venus armada might get started as soon as next year, when Rocket Lab aims to launch a privately funded probe to search for signs of organic material in the planet's clouds.

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A protein is a chain of amino acids held together by what are called peptide bonds. On their own, those bonds are extremely stable; they're estimated to have a half-life of several hundred years. But in Earth's environment, most proteins don't last nearly that long. That's because organisms have evolved a handful of ways to catalyze the break-up of peptide bonds, which have diversified into countless specialized protein-digesting enzymes. Proteases are everywhere and generally make short work of any proteins that find their way into the environment.

Now, researchers have basically short-circuited the diversification process, using AI-based protein design tools to take the catalytic core of two types of protease and replace the entire rest of the protein. The resulting enzymes could be tuned to cut specific proteins in half, and the researchers demonstrated their effectiveness by using them to cut proteins associated with neurological diseases.

Cutting proteins

The basic peptide bond isn't especially interesting-looking—it's what you get when you link an amino group to an acid, releasing a water molecule in the process. As their name implies, amino acids have both an amino and an acid group, allowing them to form peptide bonds on two sides of the amino acid. This is critical for building up the long chains found in proteins. (The amino acids also have side chains with distinctive chemistry, which gives a backbone specific properties.)

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Experts say the technology could help terrorists and nation states with production but that significant hurdles remain

In his annual speech on threats to the nation, Sir Ken McCallum, the head of the UK’s intelligence service, MI5, warned that AI had the potential to “change the stakes” on existing and even new bioweapons. Here we look at how AI might help in the development of bioweapons and the hurdles that remain.

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© Photograph: The Irkutsk Anti-Plague Research Institute of Siberia and Far East/AP

© Photograph: The Irkutsk Anti-Plague Research Institute of Siberia and Far East/AP

© Photograph: The Irkutsk Anti-Plague Research Institute of Siberia and Far East/AP

Environmentalists of all political hues must find the language and ideas that turn passion for climate action into impetus

The future of Green politics is under constant discussion after the Holborn and St Pancras byelection, but a much heavier clash – in meaning, symbolism and portent – happened earlier this summer, in King’s Lynn and West Norfolk. The council declared a climate emergency in 2021, along with hundreds of others, and while it was under Conservative control. It is now controlled by independents, and a Reform UK councillor, Austen Moore, moved to scrap the declaration.

It was the end of June, and the meeting had to be called off, because of the extreme heat in the King’s Lynn council chamber. A lot of people paused to grimly remark on that irony, but not Moore, who simply rescheduled the motion for the following week, where it was voted down (by 33 to seven). A local scientist and member of Extinction Rebellion liveblogged that debate, adding helpful maps, such as how much of the county was already below the annual flood level – most of it, including King’s Lynn itself. If this all sounds like a cheerful take home, numerous other Reform-led councils have had the same debate and Reform has prevailed. Their arguments can be terrifyingly illiterate. In Kent, councillor Linden Kemkaran asserted that climate change is fine because the world was warmer in Roman times, and as “carbon dioxide … is a trace gas essential for life on Earth”, to try to cut carbon emissions would itself be dangerous.

Zoe Williams is a Guardian columnist

Do you have an opinion on the issues raised in this article? If you would like to submit a response of up to 300 words by email to be considered for publication in our letters section, please click here.

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© Photograph: Thomas Krych/ZUMA Press Wire/Shutterstock

© Photograph: Thomas Krych/ZUMA Press Wire/Shutterstock

© Photograph: Thomas Krych/ZUMA Press Wire/Shutterstock

Kate Fleming says the government must look beyond the models it rewards today, while Jenny Haigh says unlocking potential means recognising that creativity and science are partners

Gordon Brown wants Britain to invent, invest in and own the future (British households would be £5,000 richer if we were more innovative. Let’s unleash our talents, 9 October). But invent what, and for whom? His hunt for “lost Einsteins” rests on a narrow vision: a lone genius invents, commercialisation scales, the problem is solved.

That may suit a cancer drug, but not the wicked problems of our time – social care, education, climate – which demand not silver bullets but new technologies and practices for collaboration, distributed ownership and collective innovation.

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© Photograph: Ben Birchall/PA

© Photograph: Ben Birchall/PA

© Photograph: Ben Birchall/PA

Research shows that the best linguists process unfamiliar foreign speech sounds more like non-speech sounds

If you want to get really good at French, Arabic or Hungarian, don’t start with rote learning vocabulary and grammar, focus on how they sound instead, research suggests.

A new study of how humans learn modern languages has found that the brains of the most talented linguists hear foreign terms as random noise, not words.

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© Photograph: Dimitrios Symeonidis/Alamy

© Photograph: Dimitrios Symeonidis/Alamy

© Photograph: Dimitrios Symeonidis/Alamy

When it comes to deciding the fate of the planet, Colleen Golja always thought science and reason would have a seat at the table. That was until one morning last September in London, when the climate researcher took part in the first in a series of war games. The goal: to prevent an uncontrolled global race to develop a technology aimed at cooling the planet but that comes with vast, unknown risks that could reshape life on Earth.

“I thought that would be such an easy thing. Like, we can all agree to do ethical research and make sure it's for the better of all humans,” she told WIRED. “And boy, was I wrong.”

The simulation, titled Exploring Geopolitical Tipping Points and Climate Cooling Strategies, saw a couple dozen foreign-relations experts, scientists, military personnel, and former government officials from across the world convene in a meeting room at Queen Mary University of London. After making introductions over coffee and little yogurts, they sat at tables arranged in a square with the name of the country or organization each person was playing: national governments, climate NGOs and nonprofits, indigenous groups, and tech companies. Golja was assigned to provide technical advice to help participants make scientifically literate decisions.

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US defence secretary Pete Hegseth’s plan to livestream the execution of Nidal Malik Hasan has incurred condemnation from human rights groups and politicians on all sides. But according to Coltan Scrivner, an author and psychologist at Arizona State University and expert on morbid curiosity, people are still likely to watch in large numbers. He explains why we are drawn to dark and disturbing content, and Madeleine Finlay tells Ian Sample how consuming this kind of material can harm observers’ mental health

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© Photograph: Reuters

© Photograph: Reuters

© Photograph: Reuters

Honey bees are known to leave their stingers embedded in tender flesh once they sting you and fly away. Scientists have now determined that the stinger is able to continue pumping venom into its unfortunate victim even after the bee flies away, thanks to a unique double-piston pump-like mechanism, according to a new paper published in the Proceedings of the National Academy of Sciences.

Different species have evolved different mechanisms for delivering venom, which involves piercing the skin and then pumping venom from a gland or reservoir. Spiders, for instance, have muscles surrounding their venom glands, which contract and eject venom through hollow fangs. Bees, wasps, and ants deliver venom via their stingers, either by contracting muscles around the venom reservoir or through stiff elements called lancets working together to pump venom.

Honey bees (Apis mellifera) add a unique feature: Worker bees fly away after inserting their stingers in the target, leaving the stinger behind. The stinger continues to penetrate the tissue and pump venom on its own, a rare phenomenon known as autotomy. A honey bee's stinger has three main interlocking elements that form the venom canal: a stylet that widens to form the main pumping chamber and two sharp-tipped lancets that slide back and forth, piercing the tissue and pumping venom into the target. But the precise mechanism by which the pumping action is achieved has never been directly observed.

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© Maciej A. Czyzewski/CC BY-SA 4.0

Flight was probably more widespread in dinosaurs than previously thought. A newly identified species sheds light on how some achieved liftoff.

When populations fall, fledglings can struggle to learn the right notes to attract mates. But research on how birds communicate offers hope for species’ survival

Listening to birdsong is one of life’s great joys, but when researchers heard a particular tune emerging from a tree in a Buenos Aires park, they were especially jubilant. This arrangement was among those chirped by the local rufous-collared sparrows in the 1960s, but had since disappeared from the area.

That was until scientists created a computer-generated rendition, curious to find out if birds might consider it realistic enough to imitate. Less than three months later, a local avian resident began to copy parts of the song.

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© Photograph: Martín Benchimol

© Photograph: Martín Benchimol

© Photograph: Martín Benchimol

Cambridge University study suggests stark gender divide in misdiagnosis, with women also waiting longer for treatment

Women with autoimmune conditions are up to 74% more likely than men to be told their symptoms are psychological or psychosomatic, and face much longer waits for a diagnosis and treatment, a study suggests.

Hundreds of millions of people – about one in 10 globally – are affected by autoimmune conditions, which can cause a range of health issues including fatigue, muscle pain and rashes.

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© Photograph: Bsip Sa/Alamy

© Photograph: Bsip Sa/Alamy

© Photograph: Bsip Sa/Alamy

Researchers have created a strengthened "BioPykrete" by combining ice with cellulose nanocrystals and a custom protein that binds the plant-based crystals to the ice structure. In small-scale tests, the material was about 10 times stronger than regular ice and absorbed 70 times more energy before breaking. ScienceAlert reports: Instead of wood pulp's larger, disordered fibers, the researchers used cellulose nanocrystals here. Cellulose is the main structural material in plants, and in nanocrystal form, it can act as a microscopic strengthening agent for other materials, including ice -- essentially stopping cracks from spreading easily. The protein used here was called CBM3a-AFPIII, a combination of an antifreeze protein (AFP) and a carbohydrate-binding module (CBM). Its job was to act like glue, keeping the cellulose nanocrystals and ice bonded together. It's a clever approach, and the researchers think that by tweaking their ingredients and methods, they might be able to improve their 'super ice' even further. "Optimizing solidification kinetics and freezing protocols, alongside developing diverse AFP-CBM variants, could yield even higher-strength composites," write the researchers. Besides further tests of the durability of the material, the researchers are also keen to take a closer look at how cracks propagate through BioPykrete, to confirm that the underlying strengthening mechanisms are what they think they are. Further down the line, this approach could open up a whole new landscape for materials used in packaging, construction, and more: Using a custom protein to bring two unlikely compounds (ice and cellulose) together. "By bridging the gap between recombinant protein design and structural engineering, we have developed a high-performance material specifically engineered for the rigors of the world's most extreme environments," write the researchers. The findings have been published in the journal Colloids and Surfaces B: Biointerfaces.

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Russia’s silence over the death of a lab worker underlines that pandemic preparedness amounts to nothing if information on threats is withheld

In pandemic preparedness work, scientists like to focus on the technical challenges: identifying pathogens, diagnosing infections, understanding their effects and developing vaccines and treatments. Each step promises progress through human innovation, investment and planning. The World Health Organization (WHO), for example, brings experts together to identify and prioritise emerging disease threats and collect the evidence needed to prepare for them. But preparedness depends on more than scientific innovation.

As the past week has shown, politics is the elephant in the room in all of this. No one could have predicted we would be talking about pneumonic plague, and that the death of a single lab worker in Russia would cause global headlines. It might feel like an overreaction: the WHO deals with thousands of potential disease signals worldwide every month. But the circumstances of this case are unusual given the lack of transparency from Russian authorities on what happened – and ongoing concern about biological weapons research.

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© Photograph: The Irkutsk Anti-Plague Research Institute of Siberia and Far East/AP

© Photograph: The Irkutsk Anti-Plague Research Institute of Siberia and Far East/AP

© Photograph: The Irkutsk Anti-Plague Research Institute of Siberia and Far East/AP

In an interview, Dr. Peter Piot recalled when he first saw the spindly virus under a microscope and reflected on a five-decade career spent fighting two deadly pathogens.

© Daniel Berehulak/The New York Times

Exclusive: Finds suggest account in medieval folklore of a camp near Frenni Fawr hill was rooted in reality

Magnus Maximus, the Roman emperor who ruled Britain in the fourth century, led his troops against the Picts and Scots, but a theory that he also established a military camp near Frenni Fawr hill in Wales has so far been based on folklore.

Now fourth-century coins, among other finds at a newly identified Roman fort in Pembrokeshire, suggest the medieval tale was rooted in reality, to the excitement of archaeologists.

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© Photograph: Mark Merrony

© Photograph: Mark Merrony

© Photograph: Mark Merrony

If you take a break from the gym you may lose muscle and gain fat, but it isn’t as simple as one turning into the other

‘This is not true,” says Prof Leigh Breen, a specialist in muscle physiology at the University of Leicester. But it’s a statement he hears a lot, particularly from people who have taken a long break from exercise. “They’ll often refer to the notion that their muscles have ‘softened’ or don’t feel as toned.”

The reality is that there’s no biochemistry linking the two types of tissue. Muscle and fat are distinct. “There’s no known process in the human body that would support muscle turning into fat, or vice versa,” says Breen.

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© Illustration: Edith Pritchett/The Guardian

© Illustration: Edith Pritchett/The Guardian

© Illustration: Edith Pritchett/The Guardian

A puzzle for the ages

It’s made of wood, it’s in the shape of a circle, and it is the forum for many an important gathering.

It is also the setting for today’s puzzle.

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© Photograph: BBC/Studio Lambert/Euan Cherry/PA

© Photograph: BBC/Studio Lambert/Euan Cherry/PA

© Photograph: BBC/Studio Lambert/Euan Cherry/PA

Could a drug intended to prevent painful rashes also protect our brains as we get older? The signs are promising – but not conclusive. Yet that’s enough to be driving a boom in shingles jabs

When Jenny, a 50-year-old marketing and branding professional from Cambridge, went for her shingles vaccine last year, an entirely different disease was on her mind. Having witnessed three of her four grandparents succumb to dementia, with all the distress that brought, she wants to avoid the same fate. She hopes the shingles vaccine might help.

Jenny is far from alone. Britain’s high street chemists have reported a rise in demand for the shingles vaccine, at least some of which is driven by people more worried about dementia than shingles. And while the vaccine is free for some on the NHS, most under-65s pay around £450 for the full two doses.

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© Illustration: Grace Russell/The Guardian

© Illustration: Grace Russell/The Guardian

© Illustration: Grace Russell/The Guardian

For about a decade, the mainstream understanding has been that psychedelics cause chaos in the brain. Brain networks—the stable patterns of communication that handle vision, attention, or our sense of self, and more—loosen and start talking to each other all at once. EEG traces get noisier and more complex. “Think of the networks of the brain as highways,” says Devon Stoliker, a neuroscientist at Monash University. “Under psychedelics, these highways break down into many different directions.”

In a recent Nature study, Stoliker’s team designed an experiment to test whether these directions are truly chaotic and random. Researchers gathered 62 people who had never taken a psychedelic before, gave them 19 milligrams of psilocybin, a common psychedelic found in certain fungi, and scanned their brains. Then, they used AI to analyze the drugged and sober brain scans. What emerged was not exactly chaos.

An uninterrupted trip

Stoliker thinks chaos is not a satisfactory explanation for psychedelics’ effect on the brain. “It never really explained why an individual would have a meaningful experience, why they might have insight, why they might experience clarity, and why these might translate into positive psychological changes,” Stoliker says. To investigate if there are other explanations, he and his colleagues designed a study called PsiConnect.

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© Tashi-Delek

Since the days of Dr. Alzheimer himself, there has been a dream that severe senility might have an explanation — and a cure. The search for both has never been more urgent.

© Oliver Farshi for The New York Times

The Stone Age owes its name to tools that survived to our time. The material early humans worked with most, though, was probably wood because it is so much easier to process. Unfortunately, we know very little about Paleolithic woodwork because wood rots relatively quickly. But at Abric Romaní, a rock shelter in Capellades, west of Barcelona, mineral-rich water coated wooden Neanderthal tools in a limestone-like crust. When wood rotted away, it left behind hollow molds that faithfully reflect its shape.

In a recent Science Advances study, a team of Spanish archaeologists has cataloged 597 wooden remains from Neanderthal living areas dating from 62,000 to 40,000 years ago. They found spears, digging sticks, bark trays, parts of shelters, and a club unlike anything seen before, suggesting Neanderthals were likely much more than just Homo sapiens’ dumber cousins.

Beyond hunting gear

The oldest wooden artifacts we have are mostly weapons. They include spears from a German town called Schöningen, a spear tip from Clacton-on-Sea in England, and the spear found alongside an elephant skeleton in Lehringen, Germany. Most came from waterlogged sediments, where a lack of oxygen slowed decay.

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© Gerard Campeny / IPHES-CERCA

In most cases, hotspot-driven volcanism is relatively sedate, with lava flowing down mountainsides slowly enough that people can walk out of its way. But in a number of locations—Mount Etna, Hawaii, Iceland—lava gets expelled in dramatic fountains that can reach several hundred meters in height.

Right now, we're not sure what powers them. However, thanks to a recent set of eruptions at the Kilauea volcano, we have some of the best documentation yet of erupting lava fountains. In a recent edition of Science, researchers from the US Geological Survey describe what we've seen and compare it with what we might expect based on our best ideas about what powers these fountains of molten rock.

Years of fountains

With three active volcanic regions that engage in fountaining, there has been a steady flow of dramatic videos of red-hot molten rock spouting from the Earth. But Kilauea has had only three fountaining episodes since 1823, even though it's the youngest and most active volcano in Hawaii. That activity has led to intensive study, and we have a good idea of the volcano's structure. Previous work has identified a couple of lava residues within a few kilometers of the surface, and the volcano had 35 separate data-gathering stations set up on Kilauea, including "seismic, infrasound, geodetic, gas, and visual and thermal cameras."

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© Mike Lyvers

Last month we covered the winner of Nikon's Small World in Motion video: Ning Xu of Tsinghua University in China, whose video captured tiny cilia beating in the airways of a child with a rare respiratory disorder. But allegations surfaced about Xu's use of AI while making the video. Nikon launched an investigation and concluded that Xu's entry did not comply with competition rules. The new winner is Nguyen Nam Nhat of Vietnam with a video of a tiny roundworm and a single-celled organism (above).

Founded in 2011, the Nikon Small World in Motion competition is a spinoff of the company’s Small World Photomicrography Competition, which has been around since 1974. Both are meant “to showcase the beauty and complexity of things seen through the light microscope”—one through still photographs, the other through photovideography, taking advantage of all the technological advances that now allow users to make movies or time-lapse images through the microscope.

The other winners also moved up a notch with Xu's disqualification. Benedikt Pleyer of Bavaria, Germany, placed second with a video of jellyfish larvae suspended in water droplets; Andrew Moore of Howard Hughes Medical Institute in the US placed third with a video of synchronized cell division in neighboring cells; Patrick Hickey of Hypha Research Ltd. in Edinburgh, Scotland, placed fourth with a video of the dynamics of mitochondria and chloroplasts in Turtle Vine leaf cells; and Igor Adameyko placed fifth with a video of a tiny, colorful sea slug (Cyerce kikutarobabai) on the move.

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© Nguyen Nam Nhat

The sleep disorder has been the butt of jokes and a comedic plot point, but the reality of living with narcolepsy is anything but funny. Things could be about to change for people with the condition though, after the US Food and Drug Administration (FDA) approved the first ever drug to treat narcolepsy itself, rather than just its symptoms. Madeleine Finlay tells Ian Sample how the scientific breakthrough came about, and Julie Flygare, who has narcolepsy and founded the non-profit Project Sleep, explains what it is like to live with the condition and how the drug could be gamechanger

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© Photograph: Eric Audras/Getty Images/Brand X

© Photograph: Eric Audras/Getty Images/Brand X

© Photograph: Eric Audras/Getty Images/Brand X

Some change in our lifestyles and environments over a generation has caused this increased risk. What, exactly, is a mystery

• Prof Devi Sridhar is chair of global public health at the University of Edinburgh

In the field of global health, we often talk about each generation living longer and healthier lives than their parents. We’ve seen this in the gains in life expectancy, the sharp decrease in child mortality and in the near elimination of many vaccine-preventable diseases. But since the turn of the century this progress has stalled, and in some cases several health metrics have gone backwards.

Take cancer, which was long thought to be a disease linked to old age. While most cancers do indeed still occur in elderly people, a new report highlights that a number of cancers are increasing in people who are under 50, often referred to as “early onset cancer”. The report, undertaken by the World Cancer Research Fund, looked at data from 12 different cancer types in England, the US and the Netherlands over the past 20 years. What they found isn’t pretty.

Prof Devi Sridhar is chair of global public health at the University of Edinburgh

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© Photograph: JohnnyGreig/Getty Images

© Photograph: JohnnyGreig/Getty Images

© Photograph: JohnnyGreig/Getty Images

Researchers in Vienna and Beijing have independently built the first nuclear clocks based on oscillations inside thorium nuclei, marking a major milestone for a field that could eventually produce highly portable, ultra-precise timekeepers. The clocks are already precise enough to lose only about a second over millions of years. The New York Times reports: The first nuclear clocks are not going to immediately supplant the worldwide network of atomic clocks, whose steady ticking we rely on for GPS and the definition of a second. Nor have they captured the record for most precise timepiece; the best atomic clocks are about 10,000 times more reliable and would take more than 100 billion years to lose one second. But nuclear clocks hold a bevy of potential advantages over existing atomic clocks. One day, they could be more reliable than the leading atomic versions, and nuclear clocks could be made more portable. They even hold the ability to search for certain kinds of dark matter -- the invisible stuff whose clumps make up 83 percent of the matter in the universe. If a particle of dark matter passed through the thorium nuclei, it could register as a wobble in the nuclear clock's otherwise steady ticktock. The findings have been published in the journal Nature.

Read more of this story at Slashdot.

Hundreds of new A.I.-generated findings moved the frontiers of higher math in a single day — dispelling any doubt that the field is forever changed.

© Ian C. Bates for The New York Times

OpenAI’s trove of new math results doesn’t fully solve any of these highly prestigious open questions, but it seems to make progress on some.

© Göttingen Library, Clay Mathematics Institute

We have a deep reservoir of assets, but struggle to turn small companies into global success stories. Innovation needs to be at the heart of government policy

• Gordon Brown was UK prime minister from 2007 to 2010

The coming 10 years are almost certain to be the decade that sees the greatest scientific breakthroughs in a century. The question is whether advances now under way in AI, quantum computing and biology can address cancer, find ways to treat or prevent dementia, and overcome the growing resistance to antibiotics. Can we find sustainable ways to address our energy needs and protect the environment at the same time? Can AI transform the way we deliver education, health and social care to the benefit of millions, as well as advance modern manufacturing strength? And what role can Britain’s inventors, investors and industrialists play in developing these transformative technologies?

While the US and China are the world’s obvious innovation powerhouses, the UK also has enormous assets, as the Innovation Nation Conference in Manchester addressed by the prime minister, Andy Burnham, will hear today. We are home to four of the world’s top 10 universities and 16 of the top 100, five of which are in Europe’s top 10 for spin-outs, startups based on intellectual property produced through a university’s research. With less than 1% of the world’s population, the UK produces 6% of the world’s research papers, nearly 9% of citations and 12% of the most highly cited research.

Gordon Brown was UK prime minister from 2007 to 2010

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© Photograph: Stefan Rousseau/PA Pool/AP

© Photograph: Stefan Rousseau/PA Pool/AP

© Photograph: Stefan Rousseau/PA Pool/AP