Antibody patterns in the blood may help doctors identify people at risk so they can be treated earlier, research shows

Patterns of antibodies in people’s blood could predict the onset of inflammatory bowel disease (IBD) a decade before diagnosis, according to research that raises hopes for catching the condition early.

Crohn’s disease and ulcerative colitis, the two main forms of IBD, are typically treated only after symptoms appear, when the gut has already been damaged. But scientists found that the immune system sends warning signals up to a decade before diagnosis, paving the way for potentially earlier detection and even prevention.

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© Photograph: Teodor Lazarev/Alamy

© Photograph: Teodor Lazarev/Alamy

© Photograph: Teodor Lazarev/Alamy

Judge orders government to notify her by 8pm ET Sunday whether its position changed from Friday’s court filing

Donald Trump posted on Truth Social on Sunday that “restoration work will begin” on 15 November to a historic public golf course in Washington DC despite a federal judge’s court order to pause his plans over environmental and historic preservation concerns.

US district judge Ana Reyes had ruled earlier this year that the federal government must give notice before any substantive construction work on the East Potomac golf course could proceed, and last week issued an order halting the removal of trees at the site, which she called “inexcusable”.

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© Photograph: Kevin Lamarque/Reuters

© Photograph: Kevin Lamarque/Reuters

© Photograph: Kevin Lamarque/Reuters

At least four people are confirmed to have died after a huge fire swept through the base.

The BBC's Quentin Sommerville reports from Chicago, where communities are battling a new wave of synthetic drugs.

• Injury-riddled Philadelphia fall to defeat

• Chicago hold off Atlanta comeback in QB’s return

• Browns upset Ravens in absence of Lamar Jackson

Bryce Young threw for 281 yards and two touchdowns to Tommy Tremble, and Chuba Hubbard ran for 120 yards and a score to lead the Carolina Panthers (3-2) past the injury-riddled Philadelphia Eagles (2-4). The Panthers had little trouble in the second half picking apart the Eagles, who were missing quarterback Jalen Hurts and running back Saquon Barkley. Hurts is on injured reserve and will miss at least four games with a blood clot in his calf. Tanner McKee started for Philadelphia and finished 26 of 45 for 215 yards and a touchdown.

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© Photograph: Kevin C Cox/Getty Images

© Photograph: Kevin C Cox/Getty Images

© Photograph: Kevin C Cox/Getty Images

French President Emmanuel Macron gives a national address after widespread disorder and as some looting continued in Paris.

Getting rid of head coach is not going to solve the problems that led to his appointment. Perhaps it’s worth, for once, doing something different

At the final whistle at Elland Road the TV cameras cut to a lingering shot of Manchester United chief executive, Omar Berrada, looking down pensively from the stands, deciding, it is to be hoped, on a little clemency, a re-sheathing of the managerial shotgun.

Here we have the man who hired the man. The man who fires the man. The man who also hired or rehired the previous two men he had to fire. Berrada was poached from Manchester City on the basis of his ability to grow commercial revenue (yes, OK, stop laughing), and appears, like everyone else with any actual reach around here, to exist in a strangely consequence-free bubble.

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© Photograph: Adam Vaughan/EPA

© Photograph: Adam Vaughan/EPA

© Photograph: Adam Vaughan/EPA

Noni Madueke may not have the role he wants at Arsenal but his winning goal against Nottingham Forest showed why he is one of Mikel Arteta's valued players.

Presley Gerber's death in September is being investigated as a suspected overdose.

Crystal Palace manage Pierre Sage says he feels "shame" at the Eagles' performance during their 5-0 thrashing by Brighton and does not know if he will be given time to save his job.

Wichita police awaiting toxicology results and mechanical exam of pickup truck driven by the 34-year-old woman

A woman who was arrested on Saturday after she drove a truck through a youth soccer game in Wichita, Kansas – killing a boy and a man – has been released from custody without charges pending further investigation, according to authorities.

In a statement on Sunday, the Wichita police department said investigators were awaiting the results of toxicology testing on the driver, whom the agency would only describe as a 34-year-old woman. Police said they were also waiting for “a mechanical examination” of the pickup truck that the woman was driving at the time she struck and killed six-year-old Cole Adrian and Nicholas Schafer, 35.

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© Photograph: Wyatt Glosson/KAKE-TV/AP

© Photograph: Wyatt Glosson/KAKE-TV/AP

© Photograph: Wyatt Glosson/KAKE-TV/AP

‘Meta owes us an explanation,’ group says as organizers fear censorship after account goes dark for several hours

The coalition leaders behind nationwide pro-democracy protests that have drawn millions of Americans to the streets in recent years were frustrated when its Instagram account was temporarily shut down during its latest demonstration on Saturday.

The No Kings movement’s account went dark for several hours while protests focused on increasing early voter turnout were underway, sparking censorship fears.

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© Photograph: Madison Swart/AP

© Photograph: Madison Swart/AP

© Photograph: Madison Swart/AP

New video footage of Israeli settler assault on European delegation as Netanyahu attempts to raise doubt

Hours after Israeli militants attacked a delegation of European diplomats, French clerics and a visiting mayor in the occupied West Bank, Israel’s leader, Benjamin Netanyahu, responded by questioning the delegation’s account of the assault.

“Serious accusations require serious evidence” was the all-caps headline of a social media post from the office of the prime minister. As news of the attack spread globally there was no pledge to find those accountable and bring them to justice.

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© Photograph: UGC/AFP/Getty Images

© Photograph: UGC/AFP/Getty Images

© Photograph: UGC/AFP/Getty Images

With 23 goals in seven Premier League matches, including some stunning strikes, Brighton continue to delight their fans and get them dreaming of what might be.

• Pool 4: Northampton 28-12 Cardiff

• Saints claim first win for Prem side at eighth time of asking

At 7.16pm, just around the time those Sunday night blues kick in, England’s Champions Cup cohort finally had something to cheer about. It was not pretty but after seven of their Prem rivals had failed to claim victory in the opening round of the competition, Saints survived a sizeable scare from Cardiff to put one on the board for the Prem, thanks in no small part to the excellent George Hendy.

It might be harsh on some of the performances this weekend – Gloucester were immense in drawing with Bordeaux, Exeter mightily unlucky to be beaten in Toulouse – but zero wins would have been a crushing embarrassment for a league that has been feted for its attacking exploits so far this season. One out of eight is not a lot to shout about as it is.

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© Photograph: David Davies/PA

© Photograph: David Davies/PA

© Photograph: David Davies/PA

Exclusive: Former health secretary says upfront investment in support is needed ‘if we are going to end the Neet crisis’

Ministers should cut welfare spending to fund more employment support if it wants to end the youth Neet crisis, the author of a government-led review has said.

Alan Milburn, the Tony Blair-era health secretary, told the Guardian he believed ministers should reduce benefits payments to help pay for more employment support, opening a potentially contentious debate within the Labour party over welfare cuts.

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© Photograph: Jeff Moore/PA

© Photograph: Jeff Moore/PA

© Photograph: Jeff Moore/PA

Northampton edge to a nervy Champions Cup pool win against tenacious Cardiff at Franklin's Gardens.

Hearts thought attack was the best form of defence at Celtic Park. They were badly wrong, writes Tom English.

UK home secretary’s meeting comes after PM said he wanted to rejoin European law enforcement databases

The UK home secretary, Shabana Mahmood, will meet the EU’s home affairs commissioner on Monday for further talks just days after Andy Burnham said he wanted to rejoin European law enforcement databases from which the UK has been locked out of since Brexit.

According to the European Commission, they will discuss “migration, border management, law enforcement cooperation and counter-terrorism”, with the latest Frontex data published on Monday showing a 43% decline in small boats crossing the Channel.

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© Photograph: Marcin Nowak/Anadolu/Getty Images

© Photograph: Marcin Nowak/Anadolu/Getty Images

© Photograph: Marcin Nowak/Anadolu/Getty Images

Michael Carrick said he had his headphones on this week so didn't hear the noise around Manchester United, but a 1-1 draw at Leeds means it is six games without a win.

From the attorney general stumping for Republican candidates to federal agents raiding the home of a Democratic congresswoman up for re-election, the department is violating longstanding norms

Donald Trump’s justice department has aggressively inserted itself into the midterm elections in the contest’s final weeks, shattering the department’s longstanding practice of political neutrality and leaving little doubt about the department’s willingness to help should the president attempt to subvert elections where his party is forecasted to lose seats and ultimately control of Congress.

In the last few weeks, federal agents have raided the home of a Democratic congresswoman up for re-election. It has touted criminal charges and arrests of non-citizens charged with voter fraud. The attorney general has hit the campaign trail to stump for Republican candidates. And the department gave California election officials 48 hours to investigate the citizenship of 20,000 people, and then sued the state when it refused to comply. The FBI also recently published a video criticizing Michigan senate candidate Abdul El-Sayed and other Democrats, drawing an immediate rebuke from one watchdog, who said the video “has no place in a democratic society”.

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© Composite: The Guardian/Getty Images

© Composite: The Guardian/Getty Images

© Composite: The Guardian/Getty Images

WBO heavyweight champion targets big paydays against Hrgovic, Kabayel and Itauma after second round win

Thirty minutes after Daniel Dubois had dismantled Fabio Wardley in less than two rounds on Saturday night, his promoter Frank Warren shook his head in slight awe as he described the intensity before the annihilation: “I went in the dressing room beforehand like I normally do and I couldn’t have a conversation with Daniel because he was so zoned in and focused. It showed when he got in the ring. He went out there on a seek-and-destroy mission.”

Dubois resembled a much bigger and heavier version of a young Mike Tyson as, wearing black trunks and a black cape, he walked to the ring with intense purpose. There was not a flicker of emotion as he marched quickly towards Wardley for their WBO world title rematch.

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© Photograph: Nick Potts/PA

© Photograph: Nick Potts/PA

© Photograph: Nick Potts/PA

The Pope's first event since his lung cancer diagnosis and surgery saw him recite the traditional Angelus prayer from the balcony of the Apostolic Palace.

In the face of terrible crises, it can feel right to shock people into action. But what if that has the opposite effect?

These days, it’s easy to succumb to hopelessness. Whether you’re thinking about the climate crisis, the prospect of AI apocalypse, war or political turmoil, the list of challenges facing humanity can seem insurmountable.

It certainly feels unprecedented, and much of it may be. The sense of impending doom, on the other hand, is nothing new. And what we have learned from the past is that doomerism can lead to paralysis. If everyone freezes, then nothing changes – but if we want to have a chance of mitigating some of the threats I’ve mentioned then action is what’s required.

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© Illustration: Elia Barbieri

© Illustration: Elia Barbieri

© Illustration: Elia Barbieri

• Texans 34-31 Jaguars in Wembley thriller

• Week six: Seahawks 14-17 Broncos | Email Graham

Speaking to how good they are against the run, the Jaguars have gone 22 games without allowing a rusher to go for more than 75 yards. Good luck, Woody.

Texans 0-0 Jaguars 11:08, 1st quarter

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© Photograph: Kin Cheung/AP

© Photograph: Kin Cheung/AP

© Photograph: Kin Cheung/AP

Barbican, London
Omar Rajeh performs out of frustration, resistance and a need to connect in this stream-of-consciousness solo at Dance Umbrella festival

In August 2019, Omar Rajeh sat in his bedroom, listening to the sound of pounding percussion with his world in crisis. In the midst of political instability, Citerne Beirut, a theatre and cultural centre Rajeh had founded in his native Lebanon, was forced to close, dismantled by order of the local government, who planned to build an incinerator on the site.

Rajeh tells us that as a teenager, coming of age at the end of the Lebanese civil war, dance had always seemed like the most revolutionary thing he could do. Now here he is, more than three decades later, still dancing – out of frustration, defiance, resistance and a desire to connect. As the percussive score gains momentum, Rajeh’s busy body builds up a sweat. In this danced stream of consciousness, Rajeh is not always an especially elegant mover, but he dances like it’s a necessary thing to do.

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© Photograph: Tristram Kenton/The Guardian

© Photograph: Tristram Kenton/The Guardian

© Photograph: Tristram Kenton/The Guardian

The theme before kick-off was blanks. Or, more precisely, whether either team could stop firing them at the City Ground. It was a detail to make Oliver Glasner extremely uncomfortable that his Nottingham Forest team had still to score at their own stadium this season. Arsenal, meanwhile, had drawn 0-0 on their previous two visits to this part of the east Midlands. They had only one win in five here.

Forest’s frustrations under their new manager go on. It was another spirited performance from them, bits to like, especially a full-throttle performance from Liam Delap in the No 9 position. But, for the fifth time under Glasner, there was not a goal to celebrate in front of the home support.

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© Photograph: Tom Jenkins/The Guardian

© Photograph: Tom Jenkins/The Guardian

© Photograph: Tom Jenkins/The Guardian

Capt Smit Machchhar said he screamed for help as he reached to open the cockpit door on flight FZ1073

The captain of a flydubai flight who was attacked by a co-pilot who intended to crash the plane has described ⁠blocking axe blows to his head and screaming for help as he reached to open the cockpit door.

Capt Smit ⁠Machchhar has been hailed ⁠as a ​hero for his role in averting disaster on the flight from Dubai to Tel Aviv last month, helping to thwart what the UAE ⁠attorney general has said was an attempted suicide attack by the co-pilot who had intended to crash the plane into Ben Gurion airport.

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© Photograph: Israel's Foreign Ministry/AFP/Getty Images

© Photograph: Israel's Foreign Ministry/AFP/Getty Images

© Photograph: Israel's Foreign Ministry/AFP/Getty Images

Officials allege congresswoman, whose home was raided by federal agents, or family violated law to obtain citizenship

Tom Homan, Donald Trump’s “border czar”, has said that the Republican presidential administration could “of course” strip Democratic congresswoman Ilhan Omar of her citizenship and deport her.

Homan’s comments during a Saturday appearance on Fox News were the first remarks explicitly mentioning denaturalization and deportation in connection with Omar that were attributed by name to a top Trump administration official since federal agents raided the Minnesota US House representative’s home on 12 October.

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© Photograph: J Scott Applewhite/AP

© Photograph: J Scott Applewhite/AP

© Photograph: J Scott Applewhite/AP

Philharmonic Hall, Liverpool
Mark Simpson delivers gauzy luminosity and punchy tone in Gavin Higgins’s exquisite new work, conducted with spellbinding pacing by rising star Adam Hickox alongside spirited accounts of Britten and Stravinsky

Twenty years ago, a teenager called Mark Simpson won both the BBC Young Musician of the Year and BBC Proms/Guardian Young Composer of the Year; he commissioned a short piece for clarinet from Gavin Higgins, another young composer. It was Higgins’s first paid work and he promised to thank Simpson by writing him a clarinet concerto. Fast forward two decades: both men have forged award-studded careers, Simpson continues to combine composition and performance – and Higgins has finally delivered that concerto.

Marking the end of Simpson’s tenure as the Royal Liverpool Philharmonic Orchestra’s artist in residence, its premiere featured the kind of intense splashes of musical colour that leave an afterimage. Climaxes came in slow-burn waves and paroxysms of frenetic activity. Simpson’s solo line – sometimes keening, expressive vocalise; sometimes a wild assemblage of rapid blips and riffs – weaved through the shifting orchestral textures, here haloed by muted brass, there soaring over a low hum of gong and double bass. In one exquisite passage, Simpson’s clarinet was a fine, luminous gauze. Elsewhere he punched through the vast orchestral surge through sheer focus of tone. Certain passages seemed haunted by John Adams at his most maximalist, others by Aaron Copland’s celebrated clarinet concerto. But Simpson inhabited the score as a work made to measure, the physicality of this virtuoso performance unmistakable as soloist and orchestra hurtled ecstatically to its close.

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© Photograph: Gareth Jones

© Photograph: Gareth Jones

© Photograph: Gareth Jones

Mike Huckabee calls for arrest and prosecution of those responsible as Heidi Levine, 63, recovers in hospital in Israel

The US ambassador to Israel, Mike Huckabee, has denounced the settler attack that left the Washington Post photojournalist Heidi Levine badly beaten and needing surgery as a “despicable act of terror” and called for the arrest and prosecution of those responsible.

Levine, 63, an award-winning journalist who lives in Israel, was set upon last Friday by masked Israeli settlers who used clubs and other weapons to attack Palestinian people attempting to harvest their olives in occupied West Bank towns.

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© Photograph: Ariel Schalit/AP

© Photograph: Ariel Schalit/AP

© Photograph: Ariel Schalit/AP

• Just 12.2 overs possible on first day of second Test

• Bowler seizes his opportunity with two wickets

If there is a theme to Scott Boland’s Test career, it’s making the most of limited opportunity. Finding a way into the team in 2021 when it seemed that chance had passed him by, remaining fourth in line for three spots, playing at the whim of absence, yet in those moments becoming a wrecking force, causing rashes of wickets, taking first-over strikes, threatening hat-tricks and once making good.

So began the second Test in Gqeberha, another match he wasn’t supposed to play, on a day that didn’t get 13 overs bowled, yet there he was. Making the score 20 for two. Squeezing into the game through the tiniest gap, like Eugene Tooms escaping from a cell.

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© Photograph: Themba Hadebe/AP

© Photograph: Themba Hadebe/AP

© Photograph: Themba Hadebe/AP

Two people killed and at least 17 injured as Russia and Ukraine continue to trade strikes on power infrastructure

Volodymyr Zelenskyy on Sunday thanked the Trump administration for resuming intelligence sharing between the two countries, but maintained the US had intentionally throttled its Starlink satellite internet access so that Donald Trump could send a “message” in his ongoing feud with the Ukrainian president.

In an interview on NBC, Zelenskyy said the US had “unblocked” intelligence on impending Russian ballistic missile strikes, which have pounded the country’s energy infrastructure as winter draws in.

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© Photograph: Omar Havana/AP

© Photograph: Omar Havana/AP

© Photograph: Omar Havana/AP

In the three weeks since a health worker’s death in Siberia, officials have stonewalled the WHO – setting a worrying precedent for future pandemics

Is there a plague outbreak in Russia? If the answer were a clear yes, there shouldn’t be much reason to worry. With swift medical intervention, plague is treatable. But in the nearly three weeks since a worker at a Siberian plague research unit died of a mysterious respiratory illness, state officials have been consistently tight-lipped about what happened and whether there were any further cases.

It is this uncertainty that has the World Health Organization (WHO) and international community worried: partly because there is a – very small – risk of an outbreak, and partly because it is yet another warning that the international coordination we rely on to prevent pandemics is fraying along with the rest of international politics, and could easily fail to protect us in the future.

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© Photograph: Smirnov Vladimir/Anadolu/Getty Images

© Photograph: Smirnov Vladimir/Anadolu/Getty Images

© Photograph: Smirnov Vladimir/Anadolu/Getty Images

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© Illustration: Nicola Jennings/The Guardian

© Illustration: Nicola Jennings/The Guardian

© Illustration: Nicola Jennings/The Guardian

The education secretary is right that her job is not to ‘polish the status quo’. Next, she must decide what to change first

There is a good case to be made for the increased importance of speaking skills in our new age of machines. With the UK economy’s stronger-than-expected recent performance widely linked to AI investment, it is vital that people are equipped for the kinds of in-person, public-facing jobs that are least likely to be automated. A concerning decline in children’s language development, both in the UK and internationally, has been linked to high screen use. There is a grim irony in a situation where tech companies both compete with humans for contracts and undermine our ability to talk to one other.

The Guardian has previously backed efforts to more strongly embed speaking skills, or oracy, in British schools. In a speech on Thursday, Lucy Powell promised to give them equal status to reading and writing in English (education is devolved, so her main responsibility is for England, but there are parallel initiatives in the other nations). Yet with promised updates to the national curriculum postponed, and plans for special educational needs reform causing deep anxiety to families, schools and councils, the hardest questions for the education secretary are about priorities. Following negative feedback from schools, she has also asked Ofsted to look again at its new inspection framework.

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© Photograph: Andrew Fox/Alamy

© Photograph: Andrew Fox/Alamy

© Photograph: Andrew Fox/Alamy

Anthony Goodman argues that probation officers have increasingly lost their autonomy, while Joe Sim says rehabilitation will not work in a society divided by brutal social divisions. Plus letters from Chris Parsons and Tracey Burley

Your editorial on overcrowded prisons and probation (13 October) was most welcome as it highlights a crisis in community justice that shows little sign of abating. You say that problems date back to the failed part-privatisation of the probation service, but in reality political interference has been happening for far longer than that.

Having worked for years as a prison probation officer and then in an aftercare and resettlement unit for ex-offenders, I saw good practice and ongoing practical and emotional support that demonstrated all the important points raised by Enver Solomon in his recent Guardian article.

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© Photograph: Bloomberg/Getty Images

© Photograph: Bloomberg/Getty Images

© Photograph: Bloomberg/Getty Images

Dr Denise Al Mari-de Waal and Aaron Hume call for lifelong support and an integrated care pathway that recognises the physical and mental health impacts of cerebral palsy

The sudden passing of RJ Mitte has deeply affected many people in the cerebral palsy community (RJ Mitte, actor best known for Breaking Bad, dies aged 34, 12 October). His success challenged assumptions and showed what can be achieved when people are given opportunities and support.

Yet the 165,000 people with cerebral palsy in the UK are too often underestimated. Others frequently decide what we can and cannot do without recognising our abilities, ambitions or potential.

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© Photograph: Graham Whitby Boot/Allstar

© Photograph: Graham Whitby Boot/Allstar

© Photograph: Graham Whitby Boot/Allstar

George Graham of Save the Children UK says the government has a clear opportunity to act and ensure that victims of conflict are helped

Amid allegations about advisers dealing with Roman Abramovich’s business affairs (Roman Abramovich aides falsified paperwork to disguise assets and dodge tax, records suggest, 12 October), another issue demands urgent government action – the £2.5bn from the sale of Chelsea FC, which has remained stuck in a Barclays bank account since May 2022.

The money was originally pledged to help victims of the war in Ukraine, no matter where they are in the world. Yet for over four years this huge sum of money has sat in limbo, accruing interest while victims of conflict go without desperately needed support. At a time of global aid cuts, rising food insecurity and growing humanitarian needs, the £2.5bn could make a transformative difference to the children and families we serve around the world.

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© Photograph: Martin Meissner/AP

© Photograph: Martin Meissner/AP

© Photograph: Martin Meissner/AP

Eugene Litvak says hospitals could rearrange scheduled admissions as part of efforts to prepare operationally for changes on 1 January

Your report (Millions of Medicaid recipients to face draconian requirements as of 1 January, 13 October) warns that millions may lose Medicaid coverage just as hospitals face rising uncompensated care and growing emergency department demand.

Protecting eligible patients from losing coverage through paperwork must remain the first priority. But hospitals also have a responsibility to prepare operationally for 1 January. They should not compound the coming increase in emergency demand with avoidable peaks they create themselves.

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© Photograph: The Washington Post/Getty Images

© Photograph: The Washington Post/Getty Images

© Photograph: The Washington Post/Getty Images

Bournemouth’s, and Marco Rose’s, wait for a Premier League win is over. Sunderland, locked in the bottom three, are becoming this season’s object lesson in travelling too far, too fast.

Once Kevin Danso was dismissed in the 17th minute for the denial of a goalscoring opportunity, Sunderland were sunk. If Evanilson was the match-winner with a goal, an assist and as the player Danso fouled, Régis Le Bris’s team were architects of their own downfall. “A bad day, a bad start,” the Sunderland manager said. Sixth and seventh last season, both teams have struggled domestically while cruising in the Europa League but Sunderland’s troubles deepened.

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© Photograph: Robin Jones/AFC Bournemouth/Getty Images

© Photograph: Robin Jones/AFC Bournemouth/Getty Images

© Photograph: Robin Jones/AFC Bournemouth/Getty Images

Female colleague says she was forced out shortly after incident with Luke Campbell, Hull and East Yorkshire mayor

A Reform UK mayor is under police investigation for allegedly showing “naked and sexualised” images of himself to a female member of staff.

Luke Campbell, a former Olympic boxing champion and the mayor of Hull and East Yorkshire, is understood to have been questioned under caution by Humberside police earlier this month.

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© Photograph: Phil Noble/Reuters

© Photograph: Phil Noble/Reuters

© Photograph: Phil Noble/Reuters

Ministers, officials and police under pressure over response to protests as government holds crisis talks amid ‘colossal failure of the state’

The French president, Emmanuel Macron, has criticised “unbridled violence” after one of the most violent days of unrest in years left public buildings burned, hundreds of shops destroyed and looted and at least 2,400 people arrested in cities across the country.

“Watching these images, we have all asked ourselves how could French people do this to France?” he said in a televised address.

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© Photograph: Pascal Lachenaud/AFP/Getty Images

© Photograph: Pascal Lachenaud/AFP/Getty Images

© Photograph: Pascal Lachenaud/AFP/Getty Images

What next for Michael Carrick and Manchester United? Game-wise, the answer is Wednesday’s trip to Como yet after failing, again, to double their league win tally to two, you have to wonder the destination for an already flatlining team.

This display was the latest unconvincing outing under the 45-year-old. It featured an odd formation, zero rhythm or control, and the same prevailing sense that the wheels could clatter off anytime.

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© Photograph: Lee Smith/Action Images/Reuters

© Photograph: Lee Smith/Action Images/Reuters

© Photograph: Lee Smith/Action Images/Reuters

At last, Fabian Hürzeler has the scalp that matters most to all Brighton fans and in humiliating fashion. Diego Gómez’s breathtaking goal-of-the-season contender from the halfway line, à la David Beckham, was the highlight of another hugely impressive performance from the Premier League’s top scorers as they continued their flying start to the season.

Not since a 4-1 thrashing here in February 2024 under Roberto De Zerbi had Brighton tasted victory against their arch rivals from up the A23 – a run of four matches. But having been handed the initiative by Jaydee Canvot’s own goal, a stunned Palace found themselves 3-0 down after 10 minutes. It got even worse for Pierre Sage after Brighton extended their lead through Gómez’s wonderstrike and Yasin Ayari, with Charalampos Kostoulas adding a fourth after half-time and the substitute Jack Hinshelwood’s late strike matching their record 5-0 win over Palace from 1956 in Division Three South.

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© Photograph: Rob Newell/CameraSport/Getty Images

© Photograph: Rob Newell/CameraSport/Getty Images

© Photograph: Rob Newell/CameraSport/Getty Images

It’s a perfect storm of protesters with heartfelt grievances and others set on conflict. The key here is the sense of betrayal that united them on the streets

The first thing I learned on the streets of Paris this weekend is that there is no arguing with teargas. I arrived at Place de la République just after 1pm yesterday. The mood was festive until police started firing volleys of teargas into the square from Rue du Faubourg-du-Temple.

I didn’t see the inciting incident – if there even was one – and tried walking into the cloud of CS gas hanging in the air. It was impossible. The gas clings to your nose and burns your eyes, and you quickly start struggling to breathe. I retreated towards the Boulevard de Magenta, blinking furiously to stop the stinging.

Oliver Haynes is a journalist and co-host of Sacré Bleu: the French presidential election podcast

Do you have an opinion on the issues raised in this article? If you would like to submit a response of up to 300 words by email to be considered for publication in our letters section, please click here.

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© Photograph: Abitbol Shana/ABACA/Shutterstock

© Photograph: Abitbol Shana/ABACA/Shutterstock

© Photograph: Abitbol Shana/ABACA/Shutterstock

Linbury theatre, London
Six fearless singers and the Chroma Ensemble, conducted with arresting immediacy by Naomi Woo, rise to the challenge of the brutal musical onslaughts and anarchic orchestrations of Philip Venables’ raw, imaginative score

Sarah Kane revolutionised British theatre with five provocative plays written between 1995 and 1999. Her final work, 4.48 Psychosis, was her most personal, confronting the clinical depression she struggled with for years. The play was first performed posthumously in 2000, after she died by suicide in 1999.

The Royal Opera and Guildhall School of Music and Drama commissioned Philip Venables to adapt the play as an opera, which debuted in 2016. The composer, also known for a certain “in-yer-face” approach, set Kane’s original text almost entirely, realising its 24 disjointed sections in a raw, imaginative score teeming with minimalist licks, prickly synth-pop and consoling nods to the baroque. The libretto shifts between poetic abstraction and scathing exchanges between a patient and a psychologist. An ensemble of six female singers navigates themes of depression, isolation and the agonising choices surrounding medication.

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© Photograph: Tristram Kenton/the Guardian

© Photograph: Tristram Kenton/the Guardian

© Photograph: Tristram Kenton/the Guardian

Exclusive: Play anonymously published in 1596 was collaboration between Shakespeare and Christopher Marlowe, according to computer analysis

Dramatic new evidence concludes that the play Edward III should be added to William Shakespeare’s canon, and also that it was a major collaboration with his contemporary rival Christopher Marlowe.

The history was published anonymously in 1596, and it has long been thought that Shakespeare wrote at least a few scenes. However, Dr Rory Loughnane, a leading scholar and co-author of the research, told the Guardian that computerised textual analysis pushed the case “beyond any reasonable doubt” that the Stratford-born playwright was the principal writer.

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© Photograph: Geraint Lewis/ArenaPAL

© Photograph: Geraint Lewis/ArenaPAL

© Photograph: Geraint Lewis/ArenaPAL

All the possible indications, from eye contact to body language, come with a disclaimer. The truth is, you can never be totally sure ...

I’d be far less paranoid if everyone wasn’t out to get me, so when BBC Science Focus dangled “The subtle signs somebody secretly dislikes you”, I’ve never clicked so fast. Knowledge is power, after all, and the promised signals came courtesy of psychologists via a magazine with the word science in its title.

The first indication? They avoid eye contact. Apparently “someone who repeatedly looks away, scans the room or avoids mutual gaze might be creating psychological distance”. Agreed. But they may also be checking to see who else arrives, which might not mean they secretly hate you, only that they secretly don’t like you as much as whoever just came in.

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© Photograph: posed by models; FG Trade/Getty Images

© Photograph: posed by models; FG Trade/Getty Images

© Photograph: posed by models; FG Trade/Getty Images

Scrutiny committee looks into financing of Manchester Life project as PM promises ‘full transparency’

A £55m loan to Manchester City’s Abu Dhabi owner will be investigated as part of a review into a fund for housing projects while Andy Burnham was mayor.

The prime minister has faced weeks of scrutiny over his links to Manchester City’s super-rich owners after the club was found guilty of boosting its income by £900m in a nine-year breach of financial rules.

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© Photograph: Paul Ellis/AFP/Getty Images

© Photograph: Paul Ellis/AFP/Getty Images

© Photograph: Paul Ellis/AFP/Getty Images